Relationship of flow rate, uric acid, peroxidase, and superoxide dismutase activity levels with complications in diabetic patients: Can saliva be used to diagnose diabetes?

被引：29

作者：

Zloczower, Moshe

Reznick, Abraham Z.

Zouby, Rula Obeid

Nagler, Rafael M. ^{[1
]}

机构：

[1] Rambam Med Ctr, Dept Oral & Maxillofacial Surg, Biochem Lab, Haifa, Israel

[2] Rambam Med Ctr, Salivary Clin, Haifa, Israel

[3] Rambam Med Ctr, Endocrine Dept, Haifa, Israel

[4] Rambam Med Ctr, Diabet Pregnancy Clin, Haifa, Israel

[5] Rambam Med Ctr, Dept Anat & Cell Biol, Haifa, Israel

[6] Technion Israel Inst Technol, Bruce Rappaport Fac Med, IL-31096 Haifa, Israel

来源：

ANTIOXIDANTS & REDOX SIGNALING | 2007年 / 9卷 / 06期

关键词：

D O I：

10.1089/ars.2007.1515

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Can salivary free radicals and antioxidant parameters be useful in general diagnosis and evaluation of diabetes mellitus Type II (DM)? Serum and salivary redox state of 40 diabetes mellitus patients were examined and compared with 20 controls. The involvement of salivary gland in diabetes mellitus has been suggested based on salivary flow rate and compositional alterations. In addition, the redox state of saliva of diabetes mellitus patients is different than that of normoglycemic control human subjects. This observation unveils the opportunity to use noninvasive saliva-based diagnostics for diabetes mellitus patients.

引用

页码：765 / 773

页数：9

共 21 条

[1] GLYCATION PRODUCTS AND THE PATHOGENESIS OF DIABETIC COMPLICATIONS [J].