Endocrinopathies in Children Infected with Human Immunodeficiency Virus

被引:9
作者
Loomba-Albrecht, Lindsey A. [1 ]
Bregman, Thea [2 ]
Chantry, Caroline J. [2 ]
机构
[1] Univ Calif Davis, Med Ctr, Dept Pediat, Endocrinol Sect, Sacramento, CA 95817 USA
[2] Univ Calif Davis, Med Ctr, Dept Pediat, Sacramento, CA 95817 USA
关键词
HIV; Endocrinopathy; Children; Lipodystrophy; Dyslipidemia; Insulin resistance; Thyroid; Adrenal; ACTIVE ANTIRETROVIRAL THERAPY; GROWTH-FACTOR-I; PROTEASE INHIBITOR SUBSTITUTION; HIV-ASSOCIATED LIPODYSTROPHY; METABOLIC COMPLICATIONS; INSULIN-RESISTANCE; RISK-FACTORS; PUBERTAL DEVELOPMENT; THYROID-DYSFUNCTION; BODY-COMPOSITION;
D O I
10.1016/j.ecl.2014.06.001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Endocrine changes (including adrenal insufficiency, disorders of growth and puberty, thyroid dysfunction, metabolic abnormalities and osteopenia) accompany human immunodeficiency virus (HIV) infection in pediatric patients. The cause of these changes is multifactorial and includes direct viral effects of HIV, and effects of antiretroviral therapy. These effects may be of particular importance in childhood given the critical developmental processes that occur during this time period and the likelihood of prolonged exposure to the virus and medications.
引用
收藏
页码:807 / +
页数:23
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