Lung transplant patients with coronary artery disease rarely die of cardiac causes

被引:13
作者
Makey, Ian A. [1 ]
Sui, Jin W. [2 ]
Huynh, Charles [2 ]
Das, Nitin A. [3 ]
Thomas, Mathew [1 ]
Johnson, Scott [3 ]
机构
[1] Mayo Clin, Dept Cardiothorac Surg, Jacksonville, FL 32224 USA
[2] Univ Texas Hlth San Antonio, Long Sch Med, San Antonio, TX USA
[3] Univ Texas Hlth, Dept Cardiothorac Surg, San Antonio, TX USA
关键词
atherosclerosis; heart failure; myocardial infarction; risk factors; survival; PREOPERATIVE MILD; CANDIDATES; RECIPIENTS; OUTCOMES; REVASCULARIZATION;
D O I
10.1111/ctr.13354
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: A relative contraindication for lung transplant (LT) is coronary disease burden sufficient to cause risk of myocardial infarction after LT. We analyzed cause of death and outcomes of our LT patients with coronary artery disease (CAD). Methods: Inpatient records from March 1, 2004, to January 31, 2015, were retrospectively examined and data of 306 LTs extracted. Twenty-five patients without coronary angiography (CA) and 7 with redo LTs were excluded. The other 274 patients were divided into 2 groups: CAD (n = 116) and no CAD (n = 158). Patients with prior revascularization or coronary stenosis >10% were placed into the CAD group. Results: The CAD group was older and had more male patients, greater history of smoking and hypertension, and greater proportion of patients with interstitial lung disease than the no-CAD group. CAD patients were more likely to receive a single-lung transplant. Death of cardiac causes occurred for 2 patients (1.7%) in the CAD group and for 1 patient (0.6%) in the no-CAD group (P = 0.39). Conclusions: This analysis shows that compared with patients who have no CAD, patients with CAD have different demographic characteristics and receive more single-lung transplants. Incidence of death of cardiac causes is rare.
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页数:6
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共 17 条
[11]   Coronary Artery Disease Is Under-diagnosed and Under-treated in Advanced Lung Disease [J].
Reed, Robert M. ;
Eberlein, Michael ;
Girgis, Reda E. ;
Hashmi, Salman ;
Iacono, Aldo ;
Jones, Steven ;
Netzer, Giora ;
Scharf, Steven .
AMERICAN JOURNAL OF MEDICINE, 2012, 125 (12) :1228.e13-1228.e22
[12]   Lung Transplantation and Coronary Artery Disease [J].
Sherman, William ;
Rabkin, David G. ;
Ross, David ;
Saggar, Rajan ;
Lynch, Joseph P., III ;
Belperio, John ;
Saggar, Rajeev ;
Hamilton, Michele ;
Ardehali, Abbas .
ANNALS OF THORACIC SURGERY, 2011, 92 (01) :303-308
[13]   Coronary artery disease in potential lung transplant recipients > 50 years old -: The role of coronary intervention [J].
Snell, GI ;
Richardson, M ;
Griffiths, AP ;
Williams, TJ ;
Esmore, DS .
CHEST, 1999, 116 (04) :874-879
[14]   A consensus document for the selection of lung transplant candidates: 2014-An update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation [J].
Weill, David ;
Benden, Christian ;
Corris, Paul. A. ;
Dark, John H. ;
Davis, R. Duane ;
Keshavjee, Shaf ;
Lederer, David J. ;
Mulligan, Michael. J. ;
Patterson, G. Alexander ;
Singer, Lianne G. ;
Snell, Greg I. ;
Verleden, Geert M. ;
Zamora, Martin R. ;
Glanville, Allan R. .
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2015, 34 (01) :1-15
[15]   Coronary Artery Disease in Lung Transplant Candidates: Role of Routine Invasive Assessment [J].
Wild, Johannes ;
Arrigo, Mattia ;
Isenring, Bruno Dieter ;
Buergi, Urs ;
Kurowski, Thomas ;
Schuurmans, Mace M. ;
Huber, Lars C. ;
Benden, Christian .
RESPIRATION, 2015, 89 (02) :107-111
[16]   Five-Year Outcomes with PCI Guided by Fractional Flow Reserve [J].
Xaplanteris, P. ;
Fournier, S. ;
Pijls, N. H. J. ;
Fearon, W. F. ;
Barbato, E. ;
Tonino, P. A. L. ;
Engstrom, T. ;
Kaab, S. ;
Dambrink, J-H ;
Rioufol, G. ;
Toth, G. G. ;
Piroth, Z. ;
Witt, N. ;
Frobert, O. ;
Kala, P. ;
Linke, A. ;
Jagic, N. ;
Mates, M. ;
Mavromatis, K. ;
Samady, H. ;
Irimpen, A. ;
Oldroyd, K. ;
Campo, G. ;
Rothenbuhler, M. ;
Juni, P. ;
De Bruyne, B. .
NEW ENGLAND JOURNAL OF MEDICINE, 2018, 379 (03) :250-259
[17]   Preoperative Mild-to-Moderate Coronary Artery Disease Does Not Affect Long-Term Outcomes of Lung Transplantation [J].
Zanotti, Giorgio ;
Hartwig, Matthew G. ;
Castleberry, Anthony W. ;
Martin, Jeremiah T. ;
Shaw, Linda K. ;
Williams, Judson B. ;
Lin, Shu S. ;
Davis, Robert D. .
TRANSPLANTATION, 2014, 97 (10) :1079-1085