Comprehensive analysis of oncogenic signatures and consequent repurposed drugs in TMPRSS2:ERG fusion-positive prostate cancer

被引：7

作者：

Yun, Jae Won ^{[1
]}

Lee, Sejoon ^{[2
,3
]}

Chun, Sejong ^{[4
]}

Lee, Kwang Woo ^{[5
]}

Kim, Jongsu ^{[6
]}

Kim, Hong Sook ^{[6
]}

机构：

[1] Vet Med Res Inst, Vet Hlth Serv Med Ctr, Seoul, South Korea

[2] Seoul Natl Univ, Precis Med Ctr, Bundang Hosp, Seongnam, South Korea

[3] Seoul Natl Univ, Dept Pathol & Translat Med, Bundang Hosp, Seongnam, South Korea

[4] Chonnam Natl Univ, Med Sch & Hosp, Dept Lab Med, Gwangju, South Korea

[5] Univ Queensland, Sch Med, Brisbane, Qld, Australia

[6] Sungkyunkwan Univ, Dept Biol Sci, Suwon, South Korea

来源：

CLINICAL AND TRANSLATIONAL MEDICINE | 2021年 / 11卷 / 05期

基金：

新加坡国家研究基金会;

关键词：

D O I：

10.1002/ctm2.420

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页数：6

共 8 条

[1] The oncogene ERG: a key factor in prostate cancer [J].

Adamo, P. ;

Ladomery, M. R. .

ONCOGENE, 2016, 35 (04) :403-414

[2] The TMPRSS2:ERG Fusion and Response to Androgen Deprivation Therapy for Prostate Cancer [J].

Graff, Rebecca E. ;

Pettersson, Andreas ;

Lis, Rosina T. ;

DuPre, Natalie ;

Jordahl, Kristina M. ;

Nuttall, Elizabeth ;

Rider, Jennifer R. ;

Fiorentino, Michelangelo ;

Sesso, Howard D. ;

Kenfield, Stacey A. ;

Loda, Massimo ;

Giovannucci, Edward L. ;

Rosner, Bernard ;

Nguyen, Paul L. ;

Sweeney, Christopher J. ;

Mucci, Lorelei A. .

PROSTATE, 2015, 75 (09) :897-906

[3] CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer [J].

Griffith, Malachi ;

Spies, Nicholas C. ;

Krysiak, Kilannin ;

McMichael, Joshua F. ;

Coffman, Adam C. ;

Danos, Arpad M. ;

Ainscough, Benjamin J. ;

Ramirez, Cody A. ;

Rieke, Damian T. ;

Kujan, Lynzey ;

Barnell, Erica K. ;

Wagner, Alex H. ;

Skidmore, Zachary L. ;

Wollam, Amber ;

Liu, Connor J. ;

Jones, Martin R. ;

Bilski, Rachel L. ;

Lesurf, Robert ;

Feng, Yan-Yang ;

Shah, Nakul M. ;

Bonakdar, Melika ;

Trani, Lee ;

Matlock, Matthew ;

Ramu, Avinash ;

Campbell, Katie M. ;

Spies, Gregory C. ;

Graubert, Aaron P. ;

Gangavarapu, Karthik ;

Eldred, James M. ;

Larson, David E. ;

Walker, Jason R. ;

Good, Benjamin M. ;

Wu, Chunlei ;

Su, Andrew I. ;

Dienstmann, Rodrigo ;

Margolin, Adam A. ;

Tamborero, David ;

Lopez-Bigas, Nuria ;

Jones, Steven J. M. ;

Bose, Ron ;

Spencer, David H. ;

Wartman, Lukas D. ;

Wilson, Richard K. ;

Mardis, Elaine R. ;

Griffith, Obi L. .

NATURE GENETICS, 2017, 49 (02) :170-174

[4] Analyzing and interpreting genome data at the network level with ConsensusPathDB [J].

Herwig, Ralf ;

Hardt, Christopher ;

Lienhard, Matthias ;

Kamburov, Atanas .

NATURE PROTOCOLS, 2016, 11 (10) :1889-1907

[5] TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming [J].

Iljin, Kristiina ;

Wolf, Maija ;

Edgren, Henrik ;

Gupta, Santosh ;

Kilpinen, Sami ;

Skotheim, Rolf I. ;

Peltola, Mari ;

Smit, Frank ;

Verhaegh, Gerald ;

Schalken, Jack ;

Nees, Matthias ;

Kallioniemi, Olli .

CANCER RESEARCH, 2006, 66 (21) :10242-10246

[6] Intratumoral androgen levels are linked to TMPRSS2-ERG fusion in prostate cancer [J].

Knuuttila, Matias ;

Mehmood, Arfa ;

Maki-Jouppila, Jenni ;

Ryberg, Henrik ;

Taimen, Pekka ;

Knaapila, Juha ;

Ettala, Otto ;

Bostrom, Peter J. ;

Ohlsson, Claes ;

Venalainen, Mikko S. ;

Laiho, Asta ;

Elo, Laura L. ;

Sipila, Petra ;

Makela, Sari, I ;

Poutanen, Matti .

[7] Prostate Cancer, Version 2.2019 [J].

Mohler, James L. ;

Antonarakis, Emmanuel S. ;

Armstrong, Andrew J. ;

D'Amico, Anthony, V ;

Davis, Brian J. ;

Dorff, Tanya ;

Eastham, James A. ;

Enke, Charles A. ;

Farrington, Thomas A. ;

Higano, Celestia S. ;

Horwitz, Eric Mark ;

Hurwitz, Michael ;

Ippolito, Joseph E. ;

Kane, Christopher J. ;

Kuettel, Michael R. ;

Lang, Joshua M. ;

McKenney, Jesse ;

Netto, George ;

Penson, David F. ;

Plimack, Elizabeth R. ;

Pow-Sang, Julio M. ;

Pugh, Thomas J. ;

Richey, Sylvia ;

Roach, Mack, III ;

Rosenfeld, Stan ;

Schaeffer, Edward ;

Shabsigh, Ahmad ;

Small, Eric J. ;

Spratt, Daniel E. ;

Srinivas, Sandy ;

Tward, Jonathan ;

Shead, Dorothy A. ;

Freedman-Cass, Deborah A. .

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2019, 17 (05) :479-505

[8] Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer [J].

Tomlins, SA ;

Rhodes, DR ;

Perner, S ;

Dhanasekaran, SM ;

Mehra, R ;

Sun, XW ;

Varambally, S ;

Cao, XH ;

Tchinda, J ;

Kuefer, R ;

Lee, C ;

Montie, JE ;

Shah, RB ;

Pienta, KJ ;

Rubin, MA ;

Chinnaiyan, AM .

SCIENCE, 2005, 310 (5748) :644-648

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