Serum activity of dipeptidyl peptidase IV (DPPIV; EC 3.4.14.5) in breast-fed infants with symptoms of allergy

被引：38
作者：
Jarmolowska, Beata
Bielikowicz, Krzysztof
Iwan, Malyorzata
Sidor, Katarzyna
Kostyra, Elzbieta
Kaczmarski, Maciej
机构：
[1] Univ Warmia & Mazury, PL-10719 Olsztyn, Poland
[2] Med Univ, Dept Paediat Dis 3, PL-15274 Bialystok, Poland
来源：
PEPTIDES | 2007年 / 28卷 / 03期
关键词：
beta-casomorphin; dipeptidyl peptidase IV (DPPIV); atopic dermatitis;
D O I：
10.1016/j.peptides.2006.11.014
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
beta-Casomorphins, opioid peptides present in mother's milk, are a good substrate for DPPIV (EC 3.4.14.5) which is a major factor limiting the half-life of biologically active peptides. Serum DPPIV activity of two groups of infants (healthy and atopic dermatitis) and contents of beta-casomorphin-5 and -7 in their mothers' milk were determined in the study. We have found correlation between those two parameters in the group of children with atopic dermatitis syndromes, while no such a correlation was found in the control group. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码：678 / 682
页数：5
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