Serum activity of dipeptidyl peptidase IV (DPPIV; EC 3.4.14.5) in breast-fed infants with symptoms of allergy

被引：38

作者：

Jarmolowska, Beata

Bielikowicz, Krzysztof

Iwan, Malyorzata

Sidor, Katarzyna

Kostyra, Elzbieta

Kaczmarski, Maciej

机构：

[1] Univ Warmia & Mazury, PL-10719 Olsztyn, Poland

[2] Med Univ, Dept Paediat Dis 3, PL-15274 Bialystok, Poland

来源：

PEPTIDES | 2007年 / 28卷 / 03期

关键词：

beta-casomorphin; dipeptidyl peptidase IV (DPPIV); atopic dermatitis;

D O I：

10.1016/j.peptides.2006.11.014

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

beta-Casomorphins, opioid peptides present in mother's milk, are a good substrate for DPPIV (EC 3.4.14.5) which is a major factor limiting the half-life of biologically active peptides. Serum DPPIV activity of two groups of infants (healthy and atopic dermatitis) and contents of beta-casomorphin-5 and -7 in their mothers' milk were determined in the study. We have found correlation between those two parameters in the group of children with atopic dermatitis syndromes, while no such a correlation was found in the control group. (c) 2006 Elsevier Inc. All rights reserved.

引用

页码：678 / 682

页数：5

共 42 条

[1] Weaning to hypoallergenic formula improves gut barrier function in breast-fed infants with atopic eczema [J].