Diverse roles of Eph receptors and ephrins in the regulation of cell migration and tissue assembly

被引：366
作者：
Poliakov, A [1 ]
Cotrina, M [1 ]
Wilkinson, DG [1 ]
机构：
[1] Natl Inst Med Res, Div Dev Neurobiol, London NW7 1AA, England
来源：
DEVELOPMENTAL CELL | 2004年 / 7卷 / 04期
关键词：
D O I：
10.1016/j.devcel.2004.09.006
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Eph receptor tyrosine kinases and ephrins have key roles in regulation of the migration and adhesion of cells required to form and stabilize patterns of cell organization during development. Activation of Eph receptors or ephrins can lead either to cell repulsion or to cell adhesion and invasion, and recent work has found that cells can switch between these distinct responses. This review will discuss biochemical mechanisms and developmental roles of the diverse cell responses controlled by Eph receptors and ephrins.
引用
收藏
页码：465 / 480
页数：16
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