CTX-M Type Extended Spectrum β-Lactamases in Escherichia coli Isolates From Community Acquired Upper Urinary Tract Infections at a University in the European Part of Turkey

被引：14

作者：

Celik, Aygul Dogan ^{[1
]}

Yulugkural, Zerrin ^{[1
]}

Kuloglu, Figen ^{[1
]}

Eroglu, Cafer ^{[2
]}

Torol, Sinem ^{[3
]}

Vahaboglu, Haluk ^{[3
]}

Akata, Filiz ^{[1
]}

机构：

[1] Trakya Univ, Tip Fak, Enfeksiyon Hastaliklari & Klin Mikrobiyol AD, Edirne, Turkey

[2] Ondokuz Mayis Univ, Tip Fak, Enfeksiyon Hastaliklari & Klin Mikrobiyol AD, Samsun, Turkey

[3] Kocaeli Univ, Tip Fak, Enfeksiyon Hastaliklari & Klin Mikrobiyol AD, Kocaeli, Turkey

来源：

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION | 2010年 / 43卷 / 02期

关键词：

community acquired urinary tract infection; extended spectrum beta-lactamase; Escherichia coli; ENTEROBACTERIACEAE; EPIDEMIOLOGY; SPREAD; ESBLS; PREVALENCE; EMERGENCE; STRAINS; CLONE;

D O I：

10.1016/S1684-1182(10)60026-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Extended spectrum beta-lactamase (ESBL) producing Escherichia coli has been an emerging etiologic agent in the community acquired infections. We investigated the occurrence of ESBL producing E. coli isolated from patients admitted with community acquired urinary tract infection (UTI) to the hospital of the Trakya University, Turkey during 2006. Eleven single patient isolates of E. coli harboring ESBL were identified among 30 E. coli isolated from patients admitted with symptoms corresponding to upper UTI. CTX-M type ESBLs were detected in all 11 ESBL-producers by isoelectric focusing and polymerase chain reaction screening. Sequence analysis revealed CTX-M-1 in one isolate, CTX-M-3 in three isolates and CTX-M-15 in seven isolates. ESBL-producing E. coli isolated from community acquired UTIs are widespread in the European parr of Turkey.

引用

页码：163 / 167

页数：5

共 15 条

[1] Influx of extended-spectrum β-lactamase producing enterobacteriaceae into the hospital [J].

Ben-Ami, R ;

Schwaber, MJ ;

Navon-Venezia, S ;

Schwartz, D ;

Giladi, M ;

Chmelnitsky, I ;

Leavitt, A ;

Carmeli, Y .

CLINICAL INFECTIOUS DISEASES, 2006, 42 (07) :925-934

[2] Emergence of enterobactefiaceae isolates producing CTX-M extended-spectrum β-lactamase in Austria [J].

Eisner, A ;

Fagan, EJ ;

Feierl, G ;

Kessler, HH ;

Marth, E ;

Livermore, DM ;

Woodford, N .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (02) :785-787

[3] CTX-M: changing the face of ESBLs in Europe [J].

Livermore, David M. ;

Canton, Rafael ;

Gniadkowski, Marek ;

Nordmann, Patrice ;

Rossolini, Gian Maria ;

Arlet, Guillaume ;

Ayala, Juan ;

Coque, Teresa M. ;

Kern-Zdanowicz, Izabela ;

Luzzaro, Francesco ;

Poirel, Laurent ;

Woodford, Neil .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2007, 59 (02) :165-174

[4] Spread of extended-spectrum β-lactamase CTX-M-producing Escherichia coli clinical isolates in community and nosocomial environments in Portugal [J].

Mendonca, Nuno ;

Leitao, Joana ;

Manageiro, Vera ;

Ferreira, Eugenia ;

Canica, Manuela .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (06) :1946-1955

[5] Prevalence of community-occurring extended spectrum β-lactamase-producing Enterobacteriaceae in Brazil [J].

Minarini, Luciene A. R. ;

Gales, Ana C. ;

Palazzo, Izabel C. V. ;

Darini, Ana Lucia C. .

CURRENT MICROBIOLOGY, 2007, 54 (05) :335-341

[6] Spread of Escherichia coli strains with high-level cefotaxime and ceftazidime resistance between the community, long-term care facilities, and hospital institutions [J].

Oteo, Jesus ;

Navarro, Carmen ;

Cercenado, Emilia ;

Delgado-Iribarren, Alberto ;

Wilhelmi, Isabel ;

Orden, Beatriz ;

Garcia, Carmen ;

Miguelanez, Silvia ;

Perez-Vazquez, Maria ;

Garcia-Cobos, Silvia ;

Aracil, Belen ;

Bautista, Veronica ;

Campos, Jose .

JOURNAL OF CLINICAL MICROBIOLOGY, 2006, 44 (07) :2359-2366

[7] Recommendation for treatment of severe infections caused by Enterobacteriaceae producing extended-spectrum β-lactamases (ESBLs) [J].

Paterson, DL .

CLINICAL MICROBIOLOGY AND INFECTION, 2000, 6 (09) :460-463

[8] Emergence of Enterobacteriaceae producing extended-spectrum β-lactamases (ESBLs) in the community [J].

Pitout, JDD ;

Nordmann, P ;

Laupland, KB ;

Poirel, L .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 56 (01) :52-59

[9] Epidemiology and clinical features of infections caused by extended-spectrum beta-lactamase-producing Escherichia coli in nonhospitalized patients [J].

Rodríguez-Baño, J ;

Navarro, MD ;

Romero, L ;

Martínez-Martínez, L ;

Muniain, MA ;

Perea, EJ ;

Pérez-Cano, R ;

Pascual, A .

JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (03) :1089-1094

[10] Predictors of mortality in patients with bloodstream infections caused by extended-spectrum-β-lactamase-producing enterobacteriaceae:: Importance of inadequate initial antimicrobial treatment [J].

Tumbarello, Mario ;

Sanguinetti, Maurizio ;

Montuori, Eva ;

Trecarichi, Enrico M. ;

Posteraro, Brunella ;

Fiori, Barbara ;

Citton, Rita ;

D'Inzeo, Tiziana ;

Fadda, Giovanni ;

Cauda, Roberto ;

Spanu, Teresa .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (06) :1987-1994

← 1 2 →