Dominant-negative effect of a mutant cardiac troponin T, known to cause hypertrophic cardiomyopathy, on myofibrillar structure in transgenic mice.

被引：0
|
作者：
Marian, AJ
Oberst, L
Nahm, HS
Brugada, R
Roberts, R
机构：
来源：
JOURNAL OF INVESTIGATIVE MEDICINE | 1998年 / 46卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：235A / 235A
页数：1
相关论文
共 50 条
  • [41] Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic mice
    Wen, Yuhui
    Pinto, Jose Renato
    Gomes, Aldrin V.
    Xu, Yuanyuan
    Wang, Yingcai
    Wang, Ying
    Potter, James D.
    Kerrick, W. Glenn L.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (29) : 20484 - 20494
  • [42] p53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice
    Zörnig, M
    Hueber, AO
    Evan, G
    CURRENT BIOLOGY, 1998, 8 (08) : 467 - 470
  • [43] Effects of phosphorylation on the function of human cardiac troponin I mutants that cause familial hypertrophic cardiomyopathy (fHCM) and on the structure of the human cardiac troponin (hcTn) complex
    Deppermann, S
    Yi, D
    Schmidtmann, A
    Wolf, J
    Kalbitzer, HR
    Thieleczek, R
    Jaquet, K
    BIOPHYSICAL JOURNAL, 2003, 84 (02) : 252A - 252A
  • [44] Inotropic stimulation induces cardiac dysfunction in transgenic mice expressing a troponin T (I79N) mutation linked to familial hypertrophic cardiomyopathy
    Knollmann, BC
    Blatt, SA
    Horton, K
    de Freitas, F
    Miller, T
    Bell, M
    Housmans, PR
    Weissman, NJ
    Morad, M
    Potter, JD
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (13) : 10039 - 10048
  • [45] Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant
    Andreassen, OA
    Ferrante, RJ
    Hughes, DB
    Klivenyi, P
    Dedeoglu, A
    Ona, VO
    Friedlander, RM
    Beal, MF
    JOURNAL OF NEUROCHEMISTRY, 2000, 75 (02) : 847 - 852
  • [46] TARGETED EXPRESSION OF A DOMINANT-NEGATIVE FGF RECEPTOR MUTANT IN THE EPIDERMIS OF TRANSGENIC MICE REVEALS A ROLE OF FGF IN KERATINOCYTE ORGANIZATION AND DIFFERENTIATION
    WERNER, S
    WEINBERG, W
    LIAO, X
    PETERS, KG
    BLESSING, M
    YUSPA, SH
    WEINER, RL
    WILLIAMS, LT
    EMBO JOURNAL, 1993, 12 (07): : 2635 - 2643
  • [47] F110I and R278C troponin T mutations that cause familial hypertrophic cardiomyopathy affect muscle contraction in transgenic mice and reconstituted human cardiac fibers
    Hernandez, OM
    Szczesna-Cordary, D
    Knollmann, BC
    Miller, T
    Bell, M
    Zhao, JJ
    Sirenko, SG
    Diaz, Z
    Guzman, G
    Xu, YY
    Wang, Y
    Kerrick, WGL
    Potter, JD
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (44) : 37183 - 37194
  • [48] Identification of a contractile deficit in adult cardiac myocytes expressing hypertrophic cardiomyopathy-associated mutant troponin T proteins
    Rust, EM
    Albayya, FP
    Metzger, JM
    JOURNAL OF CLINICAL INVESTIGATION, 1999, 103 (10): : 1459 - 1467
  • [49] EXPRESSION AND FUNCTIONAL ASSESSMENT OF WILD-TYPE AND A HYPERTROPHIC CARDIOMYOPATHY MUTANT CARDIAC TROPONIN-T IN QUAIL MYOTUBES
    WATKINS, HC
    SEIDMAN, CE
    SEIDMAN, JG
    FENG, HS
    SWEENEY, HL
    CIRCULATION, 1995, 92 (08) : 1111 - 1111
  • [50] Profound defect in T-cell responses in TNF-receptor-associated factor 2 dominant-negative mice.
    不详
    NATURE REVIEWS IMMUNOLOGY, 2002, 2 (10) : 721 - 721
12345