Adult Neurogenesis in Humans-Common and Unique Traits in Mammals

被引：134

作者：

Ernst, Aurelie ^{[1
,2
]}

Frisen, Jonas ^{[1
]}

机构：

[1] Karolinska Inst, Dept Cell & Mol Biol, Stockholm, Sweden

[2] German Canc Res Ctr, Div Mol Genet, Heidelberg, Germany

来源：

PLOS BIOLOGY | 2015年 / 13卷 / 01期

基金：

瑞典研究理事会;

关键词：

NEWLY GENERATED NEURONS; ENHANCED SYNAPTIC PLASTICITY; ROSTRAL MIGRATORY STREAM; NEURAL STEM-CELLS; SUBVENTRICULAR ZONE; HUMAN BRAIN; MACAQUE MONKEYS; CEREBRAL-ISCHEMIA; HUMAN HIPPOCAMPUS; PROGENITOR CELLS;

D O I：

10.1371/journal.pbio.1002045

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

New neurons are continuously generated in specific regions in the adult brain. Studies in rodents have demonstrated that adult-born neurons have specific functional features and mediate neural plasticity. Data on the extent and dynamics of adult neurogenesis in adult humans are starting to emerge, and there are clear similarities and differences compared to other mammals. Why do these differences arise? And what do they mean?

引用

页数：12

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