Gene Expression Response to Stony Coral Tissue Loss Disease Transmission in M. cavernosa and O.faveolata From Florida

被引：22

作者：

Traylor-Knowles, Nikki ^{[1
]}

Connelly, Michael T. ^{[1
]}

Young, Benjamin D. ^{[1
]}

Eaton, Katherine ^{[2
]}

Muller, Erinn M. ^{[2
]}

Paul, Valerie J. ^{[3
]}

Ushijima, Blake ^{[3
]}

DeMerlis, Allyson ^{[1
,4
]}

Drown, Melissa K. ^{[1
]}

Goncalves, Ashley ^{[1
,5
]}

Kron, Nicholas ^{[1
]}

Snyder, Grace A. ^{[1
]}

Martin, Cecily ^{[1
]}

Rodriguez, Kevin ^{[1
]}

机构：

[1] Univ Miami, Rosenstiel Sch Marine & Atmospher Sci, Dept Marine Biol & Ecol, 4600 Rickenbacker Causeway, Miami, FL 33149 USA

[2] Mote Marine Lab, Sarasota, FL 34236 USA

[3] Smithsonian Marine Stn, Ft Pierce, FL USA

[4] NOAA, Atlantic Oceanog & Meteorol Lab, Ocean Chem & Ecosyst Div, Miami, FL 33149 USA

[5] Univ Miami, Dept Biol, Coral Gables, FL 33124 USA

来源：

FRONTIERS IN MARINE SCIENCE | 2021年 / 8卷

基金：

美国国家科学基金会;

关键词：

coral reefs; Caribbean coral diseases; transcriptomics; stony coral tissue loss disease; immunity; VIBRIO-CORALLIILYTICUS; POCILLOPORA-DAMICORNIS; IMMUNITY; ASSOCIATIONS; PEROXIDASIN; PREVALENCE; PATHOGENS; SEVERITY; OUTBREAK; PATTERNS;

D O I：

10.3389/fmars.2021.681563

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Since 2014, corals within Florida's Coral Reef have been dying at an unprecedented rate due to stony coral tissue loss disease (SCTLD). Here we describe the transcriptomic outcomes of three different SCTLD transmission experiments performed at the Smithsonian Marine Station and Mote Marine Laboratory between 2019 and 2020 on the corals Orbicela faveolata and Montastraea cavernosa. Overall, diseased O. faveolata had 2194 differentially expressed genes (DEGs) compared with healthy colonies, whereas diseased M. cavernosa had 582 DEGs compared with healthy colonies. Many significant DEGs were implicated in immunity, extracellular matrix rearrangement, and apoptosis. These included, but not limited to, peroxidases, collagens, Bax-like, fibrinogen-like, protein tyrosine kinase, and transforming growth factor beta. A gene module was identified that was significantly correlated to disease transmission. This module possessed many apoptosis and immune genes with high module membership indicating that a complex apoptosis and immune response is occurring in corals during SCTLD transmission. Overall, we found that O. faveolata and M. cavernosa exhibit an immune, apoptosis, and tissue rearrangement response to SCTLD. We propose that future studies should focus on examining early time points of infection, before the presence of lesions, to understand the activating mechanisms involved in SCTLD.

引用

页数：15

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