Update on childhood rhabdomyosarcoma

被引：98

作者：

McDowell, HP ^{[1
]}

机构：

[1] RLC NHS Trust Alder Hey, Liverpool L12 2AP, Merseyside, England

来源：

ARCHIVES OF DISEASE IN CHILDHOOD | 2003年 / 88卷 / 04期

关键词：

D O I：

10.1136/adc.88.4.354

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The overall survival of childhood rhabdomyosarcoma has improved dramatically over the past 10 years. Early diagnosis and appropriate referral to a specialised centre leading to an accurate and timely diagnosis reflects on overall outcome. Recent molecular studies have identified different biological subtypes resulting in the recognition of poorer subgroups and allowing more appropriate treatment to be administered. Clinical trials remain the cornerstone to further improve outcome, now carried out on an international basis.

引用

页码：354 / 357

页数：4

共 28 条

[1]

Anderson J, 1999, GENE CHROMOSOME CANC, V26, P275, DOI 10.1002/(SICI)1098-2264(199912)26:4<275::AID-GCC1>3.3.CO

[2]

2-V

[3] Benefit of intensified therapy for patients with local or regional embryonal rhabdomyosarcoma: Results from the Intergroup Rhabdomyosarcoma Study IV [J].

Baker, KS ;

Anderson, JR ;

Link, MP ;

Grier, HE ;

Qualman, SJ ;

Maurer, HM ;

Breneman, JC ;

Wiener, ES ;

Crist, WM .

JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (12) :2427-2434

[4] Long-term outcomes after function-sparing surgery without radiotherapy for soft tissue sarcoma of the extremities and trunk [J].

Baldini, EH ;

Goldberg, J ;

Jenner, C ;

Manola, JB ;

Demetri, GD ;

Fletcher, CDM ;

Singer, S .

JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (10) :3252-3259

[5] Multiple roles of the tumor suppressor p53 [J].

Bargonetti, J ;

Manfredi, JJ .

CURRENT OPINION IN ONCOLOGY, 2002, 14 (01) :86-91

[6] Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma [J].

Barr, FG .

ONCOGENE, 2001, 20 (40) :5736-5746

[7]

BIRCH JM, 1990, CANCER-AM CANCER SOC, V66, P2239, DOI 10.1002/1097-0142(19901115)66:10<2239::AID-CNCR2820661034>3.0.CO

[8]

2-Q

[9]

Breneman JC, 2000, MED PEDIATR ONCOL, V35, P104

[10] High-dose melphalan with autologous stem-cell rescue in metastatic rhabdomyosarcoma [J].

Carli, M ;

Colombatti, R ;

Oberlin, O ;

Stevens, M ;

Masiero, L ;

Frascella, E ;

Koscielniak, E ;

Treuner, J ;

Pinkerton, CR .

JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (09) :2796-2803

← 1 2 3 →