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- [1] Ursodeoxycholic Acid Protects Against Deoxycholic Acid-Induced DNA Damage and NF-κB Activation in Barrett's Metaplasia In Vitro and In VivoGASTROENTEROLOGY, 2012, 142 (05) : S10 - S10Peng, SuiHuo, XiaofangRezai, DavoodZhang, QiuyangZhang, XiYu, ChunhuaAsanuma, KiyotakaCheng, EdaireWang, David H.Spechler, Stuart J.Souza, Rhonda F.
- [2] Deoxycholic acid causes DNA damage while inducing apoptotic resistance through NF-κB activation in benign Barrett's epithelial cellsAMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2011, 301 (02): : G278 - G286Huo, XiaofangJuergens, StefanieZhang, XiRezaei, DavoodYu, ChunhuaStrauch, Eric D.Wang, Jian-YingCheng, EdaireMeyer, FrankWang, David H.Zhang, QiuyangSpechler, Stuart J.Souza, Rhonda F.
- [3] The secondary bile acid deoxycholic acid induces activation of NF-κB in oesophageal cells in vitro.: This activation is pH-dependent and this may have clinical implications for the use of proton pump inhibitors in Barrett's metaplasiaBRITISH JOURNAL OF SURGERY, 2004, 91 : 9 - 9Harries, KJenkins, GJSDoak, SHGriffiths, APParry, JMBaxter, JN
- [4] Vitamin C inhibits nuclear factor-κB (NF-κB) activation in oesophageal cells exposed to deoxycholic acid-potential cancer preventative treatment in patients with Barrett's metaplasiaGUT, 2004, 53 : A63 - A63Harries, KJenkins, GJSDoak, SHGriffiths, APParry, JMBaxter, JN
- [5] Curcumin abrogates bile-induced NF-κB activity and DNA damage in vitro and suppresses NF-κB activity whilst promoting apoptosis in vivo, suggesting chemopreventative potential in Barrett's oesophagusCLINICAL & TRANSLATIONAL ONCOLOGY, 2012, 14 (04): : 302 - 311Rawat, NihitAlhamdani, AliMcAdam, ElizabethCronin, JamesEltahir, ZakLewis, PaulGriffiths, PaulBaxter, John N.Jenkins, Gareth J. S.
- [6] Curcumin abrogates bile-induced NF-κB activity and DNA damage in vitro and suppresses NF-κB activity whilst promoting apoptosis in vivo, suggesting chemopreventative potential in Barrett’s oesophagusClinical and Translational Oncology, 2012, 14 : 302 - 311Nihit RawatAli AlhamdaniElizabeth McAdamJames CroninZak EltahirPaul LewisPaul GriffithsJohn N. BaxterGareth J. S. Jenkins
- [7] Ursodeoxycholic acid inhibits interleukin beta 1 and deoxycholic acid-induced activation of NF-κB and AP-1 in human colon cancer cellsINTERNATIONAL JOURNAL OF CANCER, 2006, 118 (03) : 532 - 539Shah, SAVolkov, YArfin, QAbdel-Latif, MMKelleher, D
- [8] Bile acids cause DNA damage in benign Barrett's epithelial cells, which resist apoptosis through Nf-κB activationGASTROENTEROLOGY, 2008, 134 (04) : A128 - A128Hormi-Carver, KathySpechler, Stuart J.Souza, Rhonda F.
- [9] Differential effects of deoxycholic acid and ursodeoxycholic acid on apoptosis, NfκB activation, expression of COX-2 and release of vascular endothelial growth factor (Vegf) in Barrett's carcinoma cell lineGASTROENTEROLOGY, 2007, 132 (04) : A265 - A265Burnat, GregorEngel, MatthiasOcker, MatthiasHahn, Eckhart G.Konturek, Peter C.
- [10] In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acidsAMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2014, 307 (02): : G129 - G139Peng, SuiHuo, XiaofangRezaei, DavoodZhang, QiuyangZhang, XiYu, ChunhuaAsanuma, KiyotakaCheng, EdairePham, Thai H.Wang, David H.Chen, MinhuSouza, Rhonda F.Spechler, Stuart Jon