Enantioselective synthesis of planar chiral [Cr(eta(6)-arene)(CO)(3)] complexes via nucleophilic addition hydride abstraction

被引：34

作者：

Fretzen, A ^{[1
]}

Kundig, EP ^{[1
]}

机构：

[1] UNIV GENEVA,DEPT CHIM ORGAN,CH-1211 GENEVA 4,SWITZERLAND

来源：

HELVETICA CHIMICA ACTA | 1997年 / 80卷 / 06期

关键词：

D O I：

10.1002/hlca.19970800619

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Non-racemic, planar chiral 1,2-disubstituted [Cr(eta(6)-arene)(CO)(3)] complexes were obtained via external chiral ligand-controlled nucleophilic addition of alkyl-, vinyl-, and aryllithium reagents to monosubstituted complexes followed by an endo-hydride abstraction with trityl cation. The reactions with [Cr(CO)(3)(eta(6)-phenyloxazoline)], [Cr(CO)(3)(eta(6)-phenylmethaneimine)], and [Cr(CO)(3)(eta(6)-phenylmethanehydrazone)] took place with complete ortho-selectivity and a high degree of enantioselectivity (up to 98% ee).

引用

页码：2023 / 2026

页数：4

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