Genetic variations from successive whole genome sequencing during COVID-19 treatment in five individuals

被引：3
|
作者：
Hemachudha, P. [1 ,2 ]
Petcharat, S. [1 ]
Ampoot, W. [1 ]
Ponpinit, T. [1 ]
Paitoonpong, L. [3 ]
Hemachudha, T. [1 ,2 ]
机构：
[1] Chulalongkorn Univ, King Chulalongkorn Mem Hosp, Fac Med,World Hlth Organ Collaborating Ctr Res &, Thai Red Cross Emerging Infect Dis Hlth Sci Ctr, Bangkok 10330, Thailand
[2] Chulalongkorn Univ, Dept Med, Div Neurol, Bangkok, Thailand
[3] Chulalongkorn Univ, King Chulalongkorn Mem Hosp, Fac Med,Div Infect Dis,Dept Med, Thai Red Cross Emerging Infect Dis Clin Ctr, Bangkok 10330, Thailand
来源：
NEW MICROBES AND NEW INFECTIONS | 2022年 / 45卷
关键词：
next generation sequencing; SARS-CoV-2; COVID-19; genetic variations;
D O I：
10.1016/j.nmni.2022.100950
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We report multiple single nucleotide polymorphism taken at different time interval during treatment of COVID-19. Gene sequencing showed mutation within ORF1b at position P314L. Mutation at this point has been shown to impose structural remodelling that increases the affinity for remdesivir binding and may also affect binding affinity for favipiravir. (c) 2022 The Author(s). Published by Elsevier Ltd.
引用
收藏
页数：3
相关论文
共 50 条
  • [41] Data of whole genome sequencing of five garden asparagus (Asparagus officinalis) individuals with the MinION nanopore sequencer
    Tsugama, Daisuke
    Fujino, Kaien
    DATA IN BRIEF, 2020, 28
  • [42] Use of Integrative Treatment Methods by Individuals With COVID-19
    Dogan, Nurhan
    Fiskin, Gamze
    JNP- THE JOURNAL FOR NURSE PRACTITIONERS, 2022, 18 (05): : 539 - 546
  • [43] Prevalence and Factors Associated with Fear of COVID-19 Among Homeless Individuals During the COVID-19 Pandemic: Evidence from the Hamburg Survey of Homeless Individuals
    Hajek, Andre
    Bertram, Franziska
    van Rueth, Victoria
    Kretzler, Benedikt
    Pueschel, Klaus
    Heinrich, Fabian
    Konig, Hans-Helmut
    RISK MANAGEMENT AND HEALTHCARE POLICY, 2021, 14 : 2689 - 2695
  • [44] Baricitinib as the treatment of choice for hospitalised individuals with COVID-19
    Richardson, Peter J.
    Stebbing, Justin
    ECLINICALMEDICINE, 2022, 49
  • [45] Genetic and Disability Discrimination During COVID-19
    McQuillen, Meghan
    Terry, Sharon F.
    GENETIC TESTING AND MOLECULAR BIOMARKERS, 2020, 24 (12) : 759 - 760
  • [46] Loneliness during the COVID-19 pandemic: Evidence from five European countries
    Rebechi, Alessio
    Lepinteur, Anthony
    Clark, Andrew E.
    Rohde, Nicholas
    Vogele, Claus
    D'Ambrosio, Conchita
    ECONOMICS & HUMAN BIOLOGY, 2024, 55
  • [47] Genetic Variations and Seriousness of COVID-19 Patients: A Systematic Review
    Imran, Mohd.
    Abida
    Alshahrani, Ruqiah Mohammed Ahmed
    Alanazi, Ahmed Saleh
    Alnafisah, Khalid Ibrahim
    Alghorayed, Shahed Ali Mohammed
    Alsaeed, Sumaih Saeed
    Ali, Abuzer
    Alshammari, Abdulaziz Khalaf
    Min, Ho Soon
    JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2025,
  • [48] IDENTIFYING GENETIC CAUSES OF SPONTANEOUS CORONARY ARTERY DISSECTION BY WHOLE GENOME SEQUENCING IN RELATED INDIVIDUALS
    Fahey, James
    Ramialison, Mirana
    White, Anthony
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2018, 71 (11) : 123 - 123
  • [49] Viral genome sequencing for Defining Re-infection with COVID-19
    Ananthan, Velmurugan Anbu
    JOURNAL OF FAMILY MEDICINE AND PRIMARY CARE, 2021, 10 (03) : 1499 - 1500
  • [50] Genome sequencing and its use in public health responses to COVID-19
    Eden, John-Sebastian
    MICROBIOLOGY AUSTRALIA, 2021, 42 (01) : 44 - 46
12345