Recognition and treatment of autonomic disturbances in Parkinson's disease

被引:22
作者
Li, Kai [1 ]
Reichmann, Heinz [2 ]
Ziemssen, Tjalf [3 ]
机构
[1] Tech Univ Dresden, Ctr Clin Neurosci, D-01062 Dresden, Germany
[2] Tech Univ Dresden, Dept Neurol, D-01062 Dresden, Germany
[3] Tech Univ Dresden, D-01062 Dresden, Germany
关键词
autonomic dysfunction; cardiovascular; gastrointestinal; Parkinson's disease; pupil; sexual; thermoregulatory; urinary; DEEP BRAIN-STIMULATION; NEUROGENIC ORTHOSTATIC HYPOTENSION; CARDIAC SYMPATHETIC DENERVATION; SLEEP BEHAVIOR DISORDER; URINARY-TRACT SYMPTOMS; HEART-RATE-VARIABILITY; PROGRESSIVE SUPRANUCLEAR PALSY; NOCTURNAL BLOOD-PRESSURE; POWER SPECTRAL-ANALYSIS; ALPHA-SYNUCLEIN;
D O I
10.1586/14737175.2015.1095093
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Symptoms of dysautonomia are common in Parkinson's disease (PD), and almost all the functional autonomic subsystems can be involved in PD. However, they are still under-recognized in everyday clinical practice. Autonomic dysfunction can be observed in the early stages of PD, affect a substantial proportion of patients, impact quality of life and can also help in differential diagnosis. This review aims to provide an overview of the pathophysiology, clinical manifestations, relevant examination and treatment of cardiovascular, gastrointestinal, urogenital, thermoregulatory and pupil autonomic dysfunctions in Parkinson's disease.
引用
收藏
页码:1189 / 1203
页数:15
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