Stereoselective oxidation of protected inositol derivatives catalyzed by inositol dehydrogenase from Bacillus subtilis

被引：16

作者：

Daniellou, R

Phenix, CP

Tam, PH

Laliberte, MC

Palmer, DRJ

机构：

[1] Univ Saskatchewan, Dept Chem, Saskatoon, SK S7N 0W0, Canada

[2] Univ Saskatchewan, Dept Biochem, Saskatoon, SK S7N 0W0, Canada

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2005年 / 3卷 / 03期

关键词：

D O I：

10.1039/b417757f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Inositol dehydrogenase (EC 1.1.1.18) from Bacillus subtilis is shown to have a nonpolar cavity adjacent to the active site, allowing racemic protected inositol derivatives such as 4-O-benzyl-myo-inositol to be recognized with very high apparent stereoselectivity.

引用

页码：401 / 403

页数：3

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