Additive Free Fe-Catalyzed Conversion of Nitro to Aldehyde under Continuous Flow Module

被引：10

作者：

Agalave, Sandip G. ^{[1
]}

Chaudhari, Moreshwar B. ^{[1
]}

Bisht, Girish Singh ^{[1
]}

Gnanaprakasam, Boopathy ^{[1
]}

机构：

[1] Indian Inst Sci Educ & Res, Dept Chem, Pune 411008, Maharashtra, India

来源：

ACS SUSTAINABLE CHEMISTRY & ENGINEERING | 2018年 / 6卷 / 10期

关键词：

Continuous flow reactions; Fe-catalyzed reaction; Heterogeneous catalyst; Nef reaction; Nitro compounds; ASYMMETRIC CONJUGATE ADDITION; NEF REACTION; SECONDARY NITROALKANES; REDUCTION; OXIMES; OXYGEN;

D O I：

10.1021/acssuschemeng.8b02090

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fe-catalyzed direct transformation of nitro compounds to aldehyde under batch/continuous flow module is reported. This catalytic transformation is highly selective for syntheses of various aldehydes and does not require any additional additives such as bases and oxidants. Furthermore, the heterogeneous Fe-zeolite catalyst is recoverable and reusable for more than five cycles and offers gram-scale synthesis without the loss of catalytic efficiency. This heterogeneous catalyst has a maximum TOF of 5.93 h(-1).

引用

页码：12845 / 12854

页数：19

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