Synthesis of novel heterocycle systems: 6,8-dimethyl-2-(methylsulfanyl)-4-amino-substituted pyrimido[4′,5′:3,4]pyrazolo[1,5-a]pyrimidine and 9,11-dimethyl-5-(methylsulfanyl)pyrimido[2′,1′:5,1]pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine

被引：1

作者：

Hasanpour, Maede ^{[1
,2
]}

Eshghi, Hossein ^{[1
]}

Bakavoli, Mehdi ^{[1
]}

Yusefi, Mozhdeh ^{[1
]}

机构：

[1] Ferdowsi Univ Mashhad, Sch Sci, Dept Chem, Mashhad 917751436, Iran

[2] Payame Noor Univ, Dept Chem, Tehran, Iran

来源：

JOURNAL OF CHEMICAL RESEARCH | 2014年 / 11期

关键词：

pyrazolopyrimidine; triazolopyrimidine; 6,8-dimethyl-2-(methylsulfanyl)-4-amino substituted pyrimido[4 ',5 ':3,4]pyrazolo[1,5-a]pyrimidine; tetrazolopyrimidine; heterocyclic compounds; tetracyclic; cyclisation; acetylacetone; PYRAZOLO<3,4-D>PYRIMIDINES;

D O I：

10.3184/174751914X14117992793459

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The novel heterocyclic pyrimidopyrazolopyrimidine system was synthesised through cyclisation of 4-hydrazinyl-2,6-bis(methylthio) pyrimidine-5-carbonitrile with acetylacetone in high yield. Also, two other tetracyclic systems were synthesised through cyclisation of 4-hydrazinyl-6,8-dimethyl-2-(methylsulfanyl) pyrimido[4',5':3,4] pyrazolo[1,5-a] pyrimidine with triethyl orthoformate and sodium nitrite to obtain the pyrimidopyrazolotriazolo pyrimidine and pyrimidopyrazolotetrazolopyrimidine respectively.

引用

页码：643 / 647

页数：5

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