Giant vesicles containing magnetic nanoparticles and quantum dots:: Feasibility and tracking by fiber confocal fluorescence microscopy

被引:78
作者
Beaune, Gregory
Dubertret, Benoit
Clement, Olivier
Vayssettes, Catherine
Cabuil, Valerie
Menager, Christine
机构
[1] Univ Paris 06, UPMC, Equipe Colloides Inorgan, Lab Liquides Ion & Interfaces Chargees UMR 7612, F-75252 Paris, France
[2] UPR 5, Lab Opt Phys, ESPCI, F-75231 Paris, France
[3] Univ Paris 05, Lab Rech Imagerie, EA 4062, F-75015 Paris, France
关键词
fluorescence; nanoparticles; organic-inorganic hybrid composites; quantum dots; vesicles;
D O I
10.1002/anie.200700581
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) Hybrid vesicles: Magnetic nanoparticles (γ-Fe 2O3) and quantum dots (CdSe/ZnS) can be entrapped in stable vesicles by emulsion processes. The hybrid vesicles (HVs) have distinct magnetic and fluorescence properties (see images; scale bars: 10 μm). Fluorescence detection allows magnetic manipulation and tracking of the HVs in vivo by both magnetic resonance and fluorescence imaging. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:5421 / 5424
页数:4
相关论文
共 19 条
[1]   Fluorescence-modified superparamagnetic nanoparticles:: Intracellular uptake and use in cellular imaging [J].
Bertorelle, Franck ;
Wilhelm, Claire ;
Roger, Jacky ;
Gazeau, Florence ;
Menager, Christine ;
Cabuil, Valerie .
LANGMUIR, 2006, 22 (12) :5385-5391
[2]   In vivo imaging of quantum dots encapsulated in phospholipid micelles [J].
Dubertret, B ;
Skourides, P ;
Norris, DJ ;
Noireaux, V ;
Brivanlou, AH ;
Libchaber, A .
SCIENCE, 2002, 298 (5599) :1759-1762
[3]   Magnetic targeting of magnetoliposomes to solid tumors with MR imaging monitoring in mice:: Feasibility [J].
Fortin-Ripoche, JP ;
Martina, MS ;
Gazeau, F ;
Ménager, C ;
Wilhelm, C ;
Bacri, JC ;
Lesieur, S ;
Clément, O .
RADIOLOGY, 2006, 239 (02) :415-424
[4]   Luminescent polymer microcapsules addressable by a magnetic field [J].
Gaponik, N ;
Radtchenko, IL ;
Sukhorukov, GB ;
Rogach, AL .
LANGMUIR, 2004, 20 (04) :1449-1452
[5]  
Gopalakrishnan G., 2006, ANGEW CHEM, V118, P5604
[6]   Multifunctional lipid/quantum dot hybrid nanocontainers for controlled targeting of live cells [J].
Gopalakrishnan, Gopakumar ;
Danelon, Christophe ;
Izewska, Paulina ;
Prummer, Michael ;
Bolinger, Pierre-Yves ;
Geissbuehler, Isabelle ;
Demurtas, Davide ;
Dubochet, Jacques ;
Vogel, Horst .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (33) :5478-5483
[7]   A toxicologic review of quantum dots: Toxicity depends on physicochemical and environmental factors [J].
Hardman, R .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2006, 114 (02) :165-172
[8]   Fibered confocal fluorescence microscopy (Cell-viZio™) facilitates extended imaging in the field of microcirculation -: A comparison with intravital microscopy [J].
Laemmel, E ;
Genet, M ;
Le Goualher, G ;
Perchant, A ;
Le Gargasson, JF ;
Vicaut, E .
JOURNAL OF VASCULAR RESEARCH, 2004, 41 (05) :400-411
[9]   Encapsulation of magnetic and fluorescent nanoparticles in emulsion droplets [J].
Mandal, SK ;
Lequeux, N ;
Rotenberg, B ;
Tramier, M ;
Fattaccioli, J ;
Bibette, J ;
Dubertret, B .
LANGMUIR, 2005, 21 (09) :4175-4179
[10]   PREPARATION OF AQUEOUS MAGNETIC LIQUIDS IN ALKALINE AND ACIDIC MEDIA [J].
MASSART, R .
IEEE TRANSACTIONS ON MAGNETICS, 1981, 17 (02) :1247-1248