Blood pressure fluctuation and hypertension in patients with Parkinson's disease

被引:39
作者
Tsukamoto, Tetsuro [1 ]
Kitano, Yoshimi [2 ]
Kuno, Sadako [3 ]
机构
[1] Numazu Rehabil Hosp, Dept Neurol, Numazu, Shizuoka 4100813, Japan
[2] Numazu Rehabil Hosp, Dept Lab, Numazu, Shizuoka 4100813, Japan
[3] Kyoto Shijo Hosp, Dept Neurol, Shimokyo Ku, Kyoto 6000000, Japan
来源
BRAIN AND BEHAVIOR | 2013年 / 3卷 / 06期
关键词
24-h ABPM; autonomic dysfunction; fluctuating blood pressure; hypertension; Parkinson's disease; ORTHOSTATIC HYPOTENSION; CEREBROVASCULAR-DISEASE; AUTONOMIC DYSFUNCTION;
D O I
10.1002/brb3.179
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Objectives: Blood pressure (BP) abnormalities have been known in Parkinson's disease (PD) patients. The present study aimed at determining how the BPs of PD patients fluctuate in a day. Methods: A total of 37 PD patients and 44 OD (other disease) patients, all of who were inpatients, were monitored every 30 min by 24-h ambulatory blood pressure monitoring (ABPM). Results: The average systolic BP and the number of patients who showed postprandial hypotension were not different between the two groups. However, occurrence of nocturnal hypertension, BP fluctuation of over 100 mmHg in a day and BP of over 200 mmHg were significantly more frequently observed in the PD patients than in the OD patients. In the PD patients, these parameters were not different between those who were suffering from the disease for less than 10 years and those with the disease for 10 years or longer, as well as between those who had a Hoehn-Yahr staging scale of 2-3 and those with a scale of 4-5. Conclusion: Twenty-four-hour ABPM, not BP measurement once a day, enables us to determine the actual BP in PD patients. Although hypotension is a severe risk factor for falling and syncope, we emphasize the importance of monitoring rather hypertension and fluctuating BP in PD patients that may lead to a variety of other undesirable conditions. Management of hypotension, hypertension, and BP fluctuation is an important issue in the future.
引用
收藏
页码:710 / 714
页数:5
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