Nanoisland-Based Random Activation of Fluorescence for Visualizing Endocytotic Internalization of Adenovirus

被引：52

作者：

Kim, Kyujung ^{[1
]}

Choi, Joung-Woo ^{[2
]}

Ma, Kyungjae ^{[1
]}

Lee, Rimi ^{[3
]}

Yoo, Kyung-Hwa ^{[3
]}

Yun, Chae-Ok ^{[2
]}

Kim, Donghyun ^{[1
]}

机构：

[1] Yonsei Univ, Dept Elect & Elect Engn, Seoul 120749, South Korea

[2] Yonsei Univ, Coll Med, Inst Canc Res, Seoul 120752, South Korea

[3] Yonsei Univ, Dept Phys, Seoul 120742, South Korea

来源：

SMALL | 2010年 / 6卷 / 12期

关键词：

adenoviruses; fluorescence; imaging nanoislands; surface plasmons; SURFACE-PLASMON RESONANCE; LIVING CELLS; SENSITIVITY ENHANCEMENT; REFLECTION FLUORESCENCE; MICROSCOPY; LOCALIZATION; SPECTROSCOPY; BIOSENSORS; INTENSITY; MEMBRANE;

D O I：

10.1002/smll.201000058

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Super-resolution imaging is performed on metallic nanoislands by plasmonic-based activation of random near-field hot spots. Nanoislands can be synthesized to create small hotspots that spatially distinguish molecular events on the nanometer scale. Enhanced resolution is experimentally confirmed with fluorescent nanobeads, and is extended to imaging the transport of an adenovirus across a live cell membrane. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1293 / 1299

页数：7