Intracranial Metastasis from an Esophageal Gastrointestinal Stromal Tumor

被引：19

作者：

Hamada, Satoshi ^{[2
]}

Itami, Atsushi ^{[1
]}

Watanabe, Go ^{[1
]}

Nakayama, Shinya ^{[1
]}

Tanaka, Eiji ^{[1
]}

Hojo, Masato ^{[3
]}

Yoshizawa, Akihiko ^{[4
]}

Hirota, Seiichi ^{[5
]}

Sakai, Yoshiharu ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Med, Dept Surg, Kyoto, Japan

[2] Kyoto Univ, Grad Sch Med, Dept Resp Med, Kyoto, Japan

[3] Kyoto Univ, Grad Sch Med, Dept Neurosurg, Kyoto, Japan

[4] Kyoto Univ, Dept Diagnost Pathol, Kyoto, Japan

[5] Hyogo Coll Med, Dept Surg Pathol, Nishinomiya, Hyogo, Japan

来源：

INTERNAL MEDICINE | 2010年 / 49卷 / 08期

关键词：

gastrointestinal stromal tumor; brain metastasis; imatinib; mutation analysis; IMATINIB MESYLATE; C-KIT; CEREBROSPINAL-FLUID; POOR-PROGNOSIS; MUTATION; INVOLVEMENT; DELETIONS; CRITERIA;

D O I：

10.2169/internalmedicine.49.3124

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report the case of a woman with intracranial metastasis from an esophageal gastrointestinal stromal tumor (GIST) with the mutation site in the 3' end of exon 11. Frontal craniotomy was performed with complete resection of the mass, followed by postoperative stereotaxic radiotherapy (SRT). Intracranial metastasis from GISTs is extremely rare; we found only seven case reports in the literature.

引用

页码：781 / 785

页数：5

共 25 条

[21] Mesenteric gastrointestinal stromal tumour presenting as intracranial space occupying lesion
Puri T.
Gunabushanam G.
Malik M.
Goyal S.
Das A.K.
Julka P.K.
Rath G.K.
[J]. World Journal of Surgical Oncology, 4 (1)
[22] Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors
Singer, S
Rubin, BP
Lux, ML
Chen, CJ
Demetri, GD
Fletcher, CDM
Fletcher, JA
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2002, 20 (18) : 3898 - 3905
[23] Imatinib mesylate has limited activity against the central nervous system involvement of Philadelphia chromosome-positive acute lymphoblastic leukaemia due to poor penetration into cerebrospinal fluid
Takayama, N
Sato, N
O'Brien, SG
Ikeda, Y
Okamoto, SI
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 2002, 119 (01) : 106 - 108
[24] Taniguchi M, 1999, CANCER RES, V59, P4297
[25] Late resistance to imatinib therapy in a metastatic gastrointestinal stromal tumour is associated with a second KIT mutation
Wakai, T
Kanda, T
Hirota, S
Ohashi, A
Shirai, Y
Hatakeyama, K
[J]. BRITISH JOURNAL OF CANCER, 2004, 90 (11) : 2059 - 2061

← 1 2 3 →