A fully-aqueous red-fluorescent probe for selective optical sensing of Hg2+ and its application in living cells

被引：8
作者：
Pola, Murali Krishna [1 ]
Raju, Mandapati V. Ramakrishnam [1 ]
Lin, Chein-Ming [1 ]
Putikam, Raghunath [2 ]
Lin, Ming-Chang [2 ]
Epperla, Chandra Prakash [3 ]
Chang, Huan-Cheng [3 ]
Chen, San-Yuan [1 ]
Lin, Hong-Cheu [1 ]
机构：
[1] Natl Chiao Tung Univ, Dept Mat Sci & Engn, Hsinchu 300, Taiwan
[2] Natl Chiao Tung Univ, Dept Appl Chem, Ctr Interdisciplinary Mol Sci, Hsinchu 300, Taiwan
[3] Acad Sinica, Inst Atom & Mol Sci, Taipei 106, Taiwan
来源：
DYES AND PIGMENTS | 2016年 / 130卷
关键词：
Aqueous medium; Push-pull chromophore; ICT; Living cell; RATIOMETRIC DETECTION; HG(II) IONS; AMINO-ACID; MERCURY; CHEMOSENSOR; CHROMOPHORES; CHEMODOSIMETER; FLUOROPHORE; DESIGN;
D O I：
10.1016/j.dyepig.2016.03.028
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new red-fluorescent mercury ion sensor material is designed and synthesized, which is composed of at weezer-shaped hydrophilic probe containing bifurcated soft-base atoms N and S coupled with 2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran (TCF) unit. By virtue of the strong electron-accepting nature of TCF unit (as a push pull chromophore), this designed sensor material can selectively detect Hg2+ over various tested metal ions in a 100% aqueous medium via naked-eye and photoluminescence (PL) observations. Theoretical and time-resolved photoluminescence measurements further confirmed the selectivity and reversibility of the probe towards Hg2+ via intramolocular charge transfer mechanism in this sensor material. Moreover, the living cell tests by confocal fluorescence images of this sensor material towards Hg2+ were also investigated. Finally, distinguished absorption changes and fluorescence quenching spectral appearances allowed us to present the selective optical indicator of Hg2+ via TCF moiety for the first time. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：256 / 265
页数：10
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