Biosynthesis of the mitochondrial adenine nucleotide translocase (ATPase) inhibitor bongkrekic acid in Burkholderia gladioli

被引：23

作者：

Rohm, Barbara ^{[1
]}

Scherlach, Kirstin ^{[1
]}

Hertweck, Christian ^{[1
,2
]}

机构：

[1] HKI, Leibniz Inst Nat Prod Res & Infect Biol, D-07745 Jena, Germany

[2] Univ Jena, Jena, Germany

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2010年 / 8卷 / 07期

关键词：

FUNGUS RHIZOPUS-MICROSPORUS; GENE-CLUSTER; PSEUDOMONAS-COCOVENENANS; BACTERIAL ENDOSYMBIONT; TOXIN PRODUCTION; POLYKETIDE; SYMBIONT; PRODUCT; PATHWAY;

D O I：

10.1039/b925483h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Biosynthetic studies with (13)C-labelled acetates and methionine revealed that the infamous, food-related toxin bongkrekic acid from Burkholderia gladioli is a polyketide with acetate-derived beta-branches and a carboxylate terminus derived from the methyl group of an acetate.

引用

页码：1520 / 1522

页数：3

共 30 条

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