Immune reactions in different mouse strains

被引:8
|
作者
Masnaya, NV [1 ]
Churin, AA [1 ]
Borsuk, OS [1 ]
Sherstoboev, EY [1 ]
机构
[1] Russian Acad Med Sci, Siberian Branch, Tomsk Res Ctr, Inst Pharmacol, Novosibirsk, Russia
关键词
mouse strains; thymus-dependent antigen; immunocompetent cells; antibodyproducing cells; peritoneal macrophages;
D O I
10.1023/A:1021916500286
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The responses of immunocompetent cells to thymus-dependent antigen differ in mice of different strains. Immunization stimulated phagocytic activity of peritoneal macrophages in CBA/CaLac, DBA/2, and BALB/c mice and suppressed it in CC57W mice. By the formation of antibody-producing cells in the spleen in response to thymus-dependent antigen DBA/2 and CBA/CaLac mice can be classified as high responders, BALB/c mice as medium-responders, and C57B1/6 and CC57W mice as low responders.
引用
收藏
页码:376 / 378
页数:3
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