Synthesis and Tuberculostatic Activity of Some 1,2,4-Triazines

被引：12

作者：

Shchegol'kov, E. V. ^{[1
]}

Khudina, O. G. ^{[1
]}

Ivanova, A. E. ^{[1
]}

Burgart, Ya. V. ^{[1
]}

Sadchikova, E. V. ^{[2
]}

Kravchenko, M. A. ^{[3
]}

Saloutin, V. I. ^{[1
]}

机构：

[1] Russian Acad Sci, Postovsky Inst Organ Synth, Ural Branch, Ekaterinburg, Russia

[2] Ural Fed Univ, Ekaterinburg, Russia

[3] Ural Res Inst Phthisiopulmonol, Ekaterinburg, Russia

来源：

PHARMACEUTICAL CHEMISTRY JOURNAL | 2014年 / 48卷 / 06期

基金：

俄罗斯基础研究基金会;

关键词：

antituberculosis activity; 1,2,4-triazines; synthesis; DERIVATIVES; THIAZOLE;

D O I：

10.1007/s11094-014-1115-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The antituberculosis activity of dihydrotriazolo[5,1-c][1,2,4]triazines, dihydropyrazolo[5,1-c][1,2,4]triazines, dihydroimidazolo[5,1-c][1,2,4]triazines, and dihydrotetrazolo[5,1-c][1,2,4]triazines was studied. A synthetic method for convenient synthons, 3-amino-1,2,4-triazines, was proposed. Their tuberculostatic activity was investigated.

引用

页码：383 / 386

页数：4

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