ESAT and M-CHAT as screening instruments for autism spectrum disorders at 18 months in the general population: issues of overlap and association with clinical referrals

被引:7
作者
Beuker, Karin T. [1 ,2 ]
Schjolberg, Synnve [3 ]
Lie, Kari Kveim [4 ]
Swinkels, Sophie [1 ,2 ]
Rommelse, Nanda N. J. [1 ,2 ]
Buitelaar, Jan K. [2 ,5 ]
机构
[1] Radboud Univ Nijmegen Med Ctr, Nijmegen Ctr Evidence Based Practice, Dept Psychiat 966, NL-6500 HB Nijmegen, Netherlands
[2] Karakter Child & Adolescent Psychiat Univ Ctr, Nijmegen, Netherlands
[3] Norwegian Inst Publ Hlth, Div Mental Hlth, Oslo, Norway
[4] Norwegian Inst Publ Hlth, Div Epidemiol, Oslo, Norway
[5] Radboud Univ Nijmegen Med Ctr, Dept Cognit Neurosci, Nijmegen Ctr Evidence Based Practice, Nijmegen, Netherlands
关键词
ASD; M-CHAT; ESAT; Early screening; Development; Infants; MODIFIED CHECKLIST; EARLY INTERVENTION; NORWEGIAN MOTHER; PARENTS CONCERNS; CHILD COHORT; QUESTIONNAIRE; TODDLERS; DIAGNOSIS; EPILEPSY; DELAYS;
D O I
10.1007/s00787-014-0561-8
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
The Modified Checklist for Autism in Toddlers (M-CHAT) and the Early Screening of Autistic Traits (ESAT) were designed to screen for autism spectrum disorders in very young children. The aim of this study was to explore proportions of children that screened positive on the ESAT or the M-CHAT and to investigate if screening positive on the ESAT and M-CHAT is associated with clinical referral by 18 months and other aspects of children's development, health, and behavior. In this study, the mothers of 12,948 18-month-old children returned a questionnaire consisting of items from the ESAT and M-CHAT, plus questions about clinical and developmental characteristics. The M-CHAT identified more screen-positive children than the ESAT, but the ESAT was associated with more clinical referrals and tended to identify more children with medical, language, and behavioral problems. A post hoc analysis of combining the two instruments found this to be more effective than the individual instruments alone in identifying children referred to clinical services at 18 months. Further analysis at the level of single items is warranted to improve these screening instruments.
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页码:1081 / 1091
页数:11
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