Accurate methods to determine irrigation requirements are necessary for the efficient use of water in agriculture. We conducted measurements of transpiration (T) of one almond tree placed in a large weighing lysimeter and instrumented with sap-flow probes for three seasons (2014-2016; 6-9years after transplanting). We also conducted independent T estimations by the water balance method in four plots. Transpiration was related to reference evapotranspiration (ETo) to obtain the coefficient of transpiration (K-T=T/ETo). Average mid-season K-T of the lysimeter tree was 0.55, 0.68 and 0.91 in 2014, 2015, and 2016, respectively, and maximum ground cover (GC) was 55, 59 and 55% for the same years. These K-T values standardized by GC were supported by the independent estimations of K-T/GC obtained in the plots using the water balance, except in 2016, when a very high K-T value was observed in the lysimeter tree. There were significant fluctuations in daily K-T during mid-season, which we found to be related to wind speed. Furthermore, the exceptionally high K-T/GC relationship of 2016 was apparently related to the very high crop load in the lysimeter of that year (75% more than the 2 other normal years). Hourly bulk canopy conductance values were derived from lysimeter T records to confirm the high transpiration rates prior to harvest during 2016. From the K-T values measured here, we propose that the mid-season K-T of fully mature almond orchards, with a GC of 75%, should be aroundbetween 0.9 and 1.05. An estimation of evaporation from soil, which is dependent on the method of irrigation, needs to be added to obtain the net water requirements.