Evaluation and Management of Hepatocellular Carcinoma

被引:66
作者
Kulik, Laura M. [1 ]
Chokechanachaisakul, Attasit [1 ]
机构
[1] NMH, Kovler Organ Transplantat Ctr, Chicago, IL 60611 USA
关键词
Hepatocellular carcinoma; Evaluation; Management; Diagnosis; Treatment; DONOR LIVER-TRANSPLANTATION; PORTAL-VEIN EMBOLIZATION; ALPHA-FETOPROTEIN LEVELS; DRUG-ELUTING BEADS; TRANSARTERIAL CHEMOEMBOLIZATION; RADIOFREQUENCY ABLATION; HEPATIC RESECTION; INCREASED COMPLICATIONS; SURGICAL RESECTION; PROGNOSTIC-FACTORS;
D O I
10.1016/j.cld.2014.09.002
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The burden of hepatocellular carcinoma is rising and anticipated to escalate and while the best chance for long term cure remains transplantation, however the shortage of available organs remains a limitation. Liver directed therapy can serve the role of bridge/downstaging to transplant or as palliative care. Despite an improved overall survival among patients with HOC, due to advancements in surgical techniques, liver directed and systemic therapy, the 5 year overall survival remains low at 18% high-lightening the need for novel therapies. Surveillance for HOC is key to detect disease at an early stage to increase the chances for a potentially curative option.
引用
收藏
页码:23 / 43
页数:21
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