Emerging skin-picking behaviour after serotonin reuptake inhibitor-treatment in patients with obsessive-compulsive disorder: possible mechanisms and implications for clinical care
被引:11
作者:
Denys, D
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机构:
UMC, Dept Psychiat, NL-3508 GA Utrecht, NetherlandsUMC, Dept Psychiat, NL-3508 GA Utrecht, Netherlands
Denys, D
[1
]
van Megen, HJGM
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机构:
UMC, Dept Psychiat, NL-3508 GA Utrecht, NetherlandsUMC, Dept Psychiat, NL-3508 GA Utrecht, Netherlands
van Megen, HJGM
[1
]
Westenberg, HGM
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h-index: 0
机构:
UMC, Dept Psychiat, NL-3508 GA Utrecht, NetherlandsUMC, Dept Psychiat, NL-3508 GA Utrecht, Netherlands
Westenberg, HGM
[1
]
机构:
[1] UMC, Dept Psychiat, NL-3508 GA Utrecht, Netherlands
impulse control disorders;
obsessive-compulsive disorder;
pharmacotherapy;
serotonin reuptake inhibitors;
side effects;
skin-picking;
D O I:
10.1177/0269881103017001718
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Pathological skin-picking is a self-injurious, impulsive behaviour with repetitive, and ritualistic characteristics. A number of studies show that selective serotonin reuptake inhibitors (SSRIs) may be efficacious in reducing skin-picking behaviour. Two case reports are presented demonstrating that SSRI-treatment may induce or aggravate pathological skin-picking behaviour. Possible mechanisms of SSRI-induced pathological skin-picking and implications for clinical care are discussed.