A novel protein transport system involved in the biogenesis of bacterial electron transfer chains

被引：37

作者：

Berks, BC ^{[1
]}

Sargent, F

De Leeuw, E

Hinsley, AP

Stanley, NR

Jack, RL

Buchanan, G

Palmer, T

机构：

[1] Univ E Anglia, Sch Biol Sci, Ctr Metalloprot Spect & Biol, Norwich NR4 7TJ, Norfolk, England

[2] John Innes Ctr Plant Sci Res, Dept Mol Microbiol, Norwich NR4 7UH, Norfolk, England

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | 2000年 / 1459卷 / 2-3期

基金：

英国生物技术与生命科学研究理事会;

关键词：

protein transport; redox protein; metalloprotein biosynthesis; Tat pathway; Escherichia coli;

D O I：

10.1016/S0005-2728(00)00168-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Tat system is a recently discovered bacterial protein transport pathway that functions primarily in the biosynthesis of proteins containing redox active cofactors. Analogous transport systems are found in plant organelles. Remarkably and uniquely the Tat system functions to transported a diverse range of folded proteins across a biological membrane, a feat that must be achieved without rendering the membrane freely permeable to protons and other ions. Here we review the operation of the bacterial Tat system and propose a model for the structural organisation of the Tat preprotein translocase. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：325 / 330

页数：6

共 22 条

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