Macroscopic N-Halamine Biocidal Polymeric Beads

被引:18
作者
Ahmed, Abd El-Shafey I. [1 ]
Hay, John N. [1 ]
Bushell, Michael E. [1 ]
Wardell, John N. [1 ]
Cavalli, Gabriel [1 ]
机构
[1] Univ Surrey, Fac Hlth & Med Sci, Surrey GU2 7XH, England
关键词
N-halamine; beads; silica; bacteria; BIOLOGICAL-ACTIVITY; POLYSTYRENE; ALGINATE; SODIUM; IV;
D O I
10.1002/app.31774
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
The particle size of N-halamine biocidal polymers was methodically modified forming beads of different sizes by blending water-insoluble N-halamine polyurethane with sodium alginate as the matrix and loading heterocyclic rings onto modified silica gels. The biological activity of the prepared beads and halogenated modified silica derivatives was evaluated against examples of Grain-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria. The recycling possibilities and the optimum preparation conditions of the blended beads were investigated; blending prehalogenated polyurethane (5%, w/v) with sodium alginate (3%, w/v) followed by crosslinking with CaCl2 (10%, w/v) at 40 degrees C are the optimum preparation conditions for the alginate beads. (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 116: 2396-2408, 2010
引用
收藏
页码:2396 / 2408
页数:13
相关论文
共 26 条
[1]   Biocidal polymers (I): Preparation and biological activity of some novel blocidal polymers based on uramil and its azo-dyes [J].
Ahmed, A. E. I. ;
Hay, J. N. ;
Bushell, M. E. ;
Wardell, J. N. ;
Cavalli, G. .
REACTIVE & FUNCTIONAL POLYMERS, 2008, 68 (01) :248-260
[2]   Biocidal polymers (II): Determination of biological activity of novel N-halamine biocidal polymers and evaluation for use in water filters [J].
Ahmed, Abd El-Shafey I. ;
Hay, John N. ;
Bushell, Michael E. ;
Wardell, John N. ;
Cavalli, Gabriel .
REACTIVE & FUNCTIONAL POLYMERS, 2008, 68 (10) :1448-1458
[3]   Optimizing Halogenation Conditions of N-Halamine Polymers and Investigating Mode of Bactericidal Action [J].
Ahmed, Abd El-Shafey I. ;
Hay, John N. ;
Bushell, Michael E. ;
Wardell, John N. ;
Cavalli, Gabriel .
JOURNAL OF APPLIED POLYMER SCIENCE, 2009, 113 (04) :2404-2412
[4]   Cross-linked alginate-gelatine beads: a new matrix for controlled release of pindolol [J].
Almeida, PF ;
Almeida, AJ .
JOURNAL OF CONTROLLED RELEASE, 2004, 97 (03) :431-439
[5]   Synthesis and antimicrobial applications of 5,5′-ethylenebis[5-methyl-3-(3-triethoxysilylpropyl)hydantoin] [J].
Barnes, Kevin ;
Liang, J. ;
Wu, R. ;
Worley, S. D. ;
Lee, J. ;
Broughton, R. M. ;
Huang, T. S. .
BIOMATERIALS, 2006, 27 (27) :4825-4830
[6]   N-Halamine-based chitosan: Preparation, characterization, and antimicrobial function [J].
Cao, Zhengbing ;
Sun, Yuyu .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2008, 85A (01) :99-107
[7]   Biocidal polystyrene beads.: III.: Comparison of N-halamine and quat functional groups [J].
Chen, Y ;
Worley, SD ;
Huang, TS ;
Weese, J ;
Kim, J ;
Wei, CI ;
Williams, JF .
JOURNAL OF APPLIED POLYMER SCIENCE, 2004, 92 (01) :363-367
[8]   Biocidal polystyrene beads. IV. Functionalized methylated polystyrene [J].
Chen, Y ;
Worley, SD ;
Huang, TS ;
Weese, J ;
Kim, J ;
Wei, CI ;
Williams, JF .
JOURNAL OF APPLIED POLYMER SCIENCE, 2004, 92 (01) :368-372
[9]   Synthesis, characterization, and antibacterial activities of novel N-halamine copolymers [J].
Chen, Ying ;
Wang, Li ;
Yu, Haojie ;
Shi, Quan ;
Dong, Xiaochen .
JOURNAL OF MATERIALS SCIENCE, 2007, 42 (11) :4018-4024
[10]   Biocidal poly(styrenehydantoin) beads for disinfection of water [J].
Chen, YJ ;
Worley, SD ;
Kim, J ;
Wei, CI ;
Chen, TY ;
Santiago, JI ;
Williams, JF ;
Sun, G .
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2003, 42 (02) :280-284