Complications of Immunosuppressive Therapy in Solid Organ Transplantation

被引：53

作者：

Katabathina, Venkata ^{[1
]}

Menias, Christine O. ^{[2
]}

Pickhardt, Perry ^{[3
]}

Lubner, Meghan ^{[3
]}

Prasad, Srinivasa R. ^{[4
]}

机构：

[1] Univ Texas Hlth Sci Ctr San Antonio, Dept Radiol, 7703 Floyd Curl Dr, San Antonio, TX 78229 USA

[2] Mayo Clin, Dept Radiol, 13400 E Shea Blvd, Scottsdale, AZ 85259 USA

[3] Univ Wisconsin, Dept Radiol, G3-310 600 Highland Ave, Madison, WI 53792 USA

[4] Univ Texas MD Anderson Canc Ctr, Dept Radiol, 1400 Pressler St, Houston, TX 77030 USA

来源：

RADIOLOGIC CLINICS OF NORTH AMERICA | 2016年 / 54卷 / 02期

关键词：

Immunosuppression; Complications; Transplantation; Infections; Malignancy; Computed tomography; Posttransplant lymphoproliferative disorder (PTLD); MR imaging; POSTTRANSPLANTATION LYMPHOPROLIFERATIVE DISORDER; MYCOBACTERIUM-TUBERCULOSIS INFECTION; FUNGAL-INFECTIONS; CT FINDINGS; PULMONARY ASPERGILLOSIS; PNEUMOCYSTIS PNEUMONIA; INVASIVE ASPERGILLOSIS; LIVER-TRANSPLANTATION; NOCARDIA INFECTION; MEDICAL PROGRESS;

D O I：

10.1016/j.rcl.2015.09.009

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Availability of novel immunosuppressive drugs is the most important factor responsible for significant improvement in long-term graft survival rates after solid organ transplantation. However, chronic immunosuppression predisposes patients to a myriad of potentially life-threatening complications. In addition to drug-related adverse effects, transplant recipients are at increased risk of developing opportunistic microbial infections and a spectrum of unique cancers, many of which are caused by oncogenic viruses. Cross-sectional imaging studies play a crucial role in the timely diagnosis and management of post-transplant infections and malignancies.

引用

页码：303 / +

页数：19

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