Does autoreactivity have a role in narcolepsy?

被引：15

作者：

Partinen, Markku ^{[1
,2
]}

Kornum, Birgitte Rahbek ^{[4
,5
]}

Plazzi, Giuseppe ^{[6
,7
]}

Jennum, Poul ^{[5
]}

Julkunen, Ilkka ^{[8
,9
]}

Vaarala, Outi ^{[3
,10
]}

机构：

[1] Vitalmed Res Ctr, Helsinki Sleep Clin, Helsinki, Finland

[2] Univ Helsinki, Dept Clin Neurosci, Helsinki, Finland

[3] Univ Helsinki, Inst Clin Med, Helsinki, Finland

[4] Univ Copenhagen, Dept Diagnost, Mol Sleep Lab, Glostrup Hosp, Glostrup, Denmark

[5] Univ Copenhagen, Glostrup Hosp, Dept Clin Neurophysiol, Danish Ctr Sleep Med, Glostrup, Denmark

[6] Univ Bologna, Dept Biomed & Neuromotor Sci, I-40126 Bologna, Italy

[7] IRCCS Ist Sci Neurol, Bologna, Italy

[8] Univ Turku, Dept Virol, Turku, Finland

[9] Natl Inst Hlth & Welf, Dept Infect Dis Surveillance & Control, Helsinki, Finland

[10] AstraZeneca, Resp Inflammatory & Autoimmune Dis, Innovat Med, Molndal, Sweden

来源：

LANCET NEUROLOGY | 2014年 / 13卷 / 11期

关键词：

D O I：

10.1016/S1474-4422(14)70168-1

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：1072 / 1073

页数：2

共 4 条

[1] Narcolepsy patients have antibodies that stain distinct cell populations in rat brain and influence sleep patterns [J].

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Julkunen, Ilkka ;

Horvath, Beata ;

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Kalmar, Lajos ;

Bagdy, Gyorgy ;

Huutoniemi, Anne ;

Partinen, Markku ;

Hokfelt, Tomas .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (35) :E3735-E3744

[2] CD4+ T cell Autoimmunity to Hypocretin/Orexin and Cross-Reactivity to a 2009 H1N1 Influenza A Epitope in Narcolepsy(Retraction of vol 5, 216ra176, 2013) [J].

De la Herran-Arita, Alberto K. ;

Kornum, Birgitte Rahbek ;

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Jiang, Wei ;

Lin, Ling ;

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Macaubas, Claudia ;

Einen, Mali ;

Plazzi, Giuseppe ;

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SCIENCE TRANSLATIONAL MEDICINE, 2014, 6 (247)

[3] Passive transfer of narcolepsy: Anti-TRIB2 autoantibody positive patient IgG causes hypothalamic orexin neuron loss and sleep attacks in mice [J].

Katzav, Aviva ;

Arango, Maria T. ;

Kivity, Shaye ;

Tanaka, Susumu ;

Givaty, Gili ;

Agmon-Levin, Nancy ;

Honda, Makoto ;

Anaya, Juan-Manuel ;

Chapman, Joab ;

Shoenfeld, Yehuda .

JOURNAL OF AUTOIMMUNITY, 2013, 45 :24-30

[4] Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination [J].

Partinen, Markku ;

Kornum, Birgitte Rahbek ;

Plazzi, Giuseppe ;

Jennum, Poul ;

Julkunen, Ilkka ;

Vaarala, Outi .

LANCET NEUROLOGY, 2014, 13 (06) :600-613

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