In Situ Synthesis of Block Copolymer Nanoassemblies via Polymerization-Induced Self-Assembly in Poly(ethylene glycol)

被引：96
作者：
Gao, Chengqiang [1 ]
Zhou, Heng [1 ]
Qu, Yaqing [1 ]
Wang, Wei [1 ]
Khan, Habib [1 ]
Zhang, Wangqing [1 ,2 ]
机构：
[1] Nankai Univ, Inst Polymer Chem, Minist Educ, Key Lab Funct Polymer Mat, Tianjin 300071, Peoples R China
[2] Nankai Univ, Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China
来源：
MACROMOLECULES | 2016年 / 49卷 / 10期
基金：
美国国家科学基金会;
关键词：
RAFT DISPERSION POLYMERIZATION; ONE-POT SYNTHESIS; NANO-OBJECTS; POLYETHYLENE-GLYCOL; MOLECULAR-WEIGHT; GREEN SOLVENT; VESICLES; NANOPARTICLES; MORPHOLOGIES; AGENT;
D O I：
10.1021/acs.macromol.6b00688
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
A new formulation of polymerization-induced self-assembly in poly(ethylene glycol) (PEG) named PEG-PISA to synthesize diblock copolymer nanoassemblies via macromolecular RAFT agent mediated dispersion polymerization is reported. In PEG-PISA, the viscous PEG with molecular weight ranging from 200 to 1000 Da is used as polymerization medium. The utilization of the viscous PEG as the polymerization medium affords the advantages including, fast polymerization rate, good control over the synthesis of diblock copolymers, and in situ synthesis of both amphiphilic and doubly hydrophobic diblock copolymer nanoassemblies at polymer concentration of up to 50%. Also ascribed to the viscous polymerization medium of PEG, two new and/or interesting diblock copolymer nano assemblies of ellipsoidal vesicles and nanotubes are formed via PEG-PISA, and the reason on formation of ellipsoidal vesicles and nanotubes is discussed. The proposed PEG-PISA is anticipated to be an effective method to synthesize block copolymer nanoassemblies combining the advantages of alcoholic/aqueous PISA and versatility of poly(ethylene glycol).
引用
收藏
页码：3789 / 3798
页数：10
相关论文
共 74 条
[1]   Polymerization-induced self-assembly driving chiral nanostructured materials [J].
Bauri, Kamal ;
Narayanan, Amal ;
Haldar, Ujjal ;
De, Priyadarsi .
POLYMER CHEMISTRY, 2015, 6 (34) :6152-6162
[2]   Mechanistic Insights for Block Copolymer Morphologies: How Do Worms Form Vesicles? [J].
Blanazs, Adam ;
Madsen, Jeppe ;
Battaglia, Giuseppe ;
Ryan, Anthony J. ;
Armes, Steven P. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (41) :16581-16587
[3]   In Situ Formation of Polymer-Gold Composite Nanoparticles with Tunable Morphologies [J].
Bleach, Richard ;
Karagoz, Bunyamin ;
Prakash, Shyam M. ;
Davis, Thomas P. ;
Boyer, Cyrille .
ACS MACRO LETTERS, 2014, 3 (07) :591-596
[4]   Polyethylene glycol and solutions of polyethylene glycol as green reaction media [J].
Chen, J ;
Spear, SK ;
Huddleston, JG ;
Rogers, RD .
GREEN CHEMISTRY, 2005, 7 (02) :64-82
[5]   Polymerization-induced self-assembly of block copolymer nanoparticles via RAFT non-aqueous dispersion polymerization [J].
Derry, Matthew J. ;
Fielding, Lee A. ;
Armes, Steven P. .
PROGRESS IN POLYMER SCIENCE, 2016, 52 :1-18
[6]   Industrially-relevant polymerization-induced self-assembly formulations in non-polar solvents: RAFT dispersion polymerization of benzyl methacrylate [J].
Derry, Matthew J. ;
Fielding, Lee A. ;
Armes, Steven P. .
POLYMER CHEMISTRY, 2015, 6 (16) :3054-3062
[7]   An atom transfer radical polymerization system: catalyzed by an iron catalyst in PEG-400 [J].
Ding, Mingqiang ;
Jiang, Xiaowu ;
Peng, Jinying ;
Zhang, Lifen ;
Cheng, Zhenping ;
Zhu, Xiulin .
GREEN CHEMISTRY, 2015, 17 (01) :271-278
[8]   Macro-RAFT agent mediated dispersion polymerization: the monomer concentration effect on the morphology of the in situ synthesized block copolymer nano-objects [J].
Ding, Zhonglin ;
Gao, Chengqiang ;
Wang, Shuang ;
Liu, Hui ;
Zhang, Wangqing .
POLYMER CHEMISTRY, 2015, 6 (46) :8003-8011
[9]   Polymerization induced self-assembly: tuning of nano-object morphology by use of CO2 [J].
Dong, Siming ;
Zhao, Wei ;
Lucien, Frank P. ;
Perrier, Sebastien ;
Zetterlund, Per B. .
POLYMER CHEMISTRY, 2015, 6 (12) :2249-2254
[10]   RAFT dispersion polymerization in non-polar solvents: facile production of block copolymer spheres, worms and vesicles in n-alkanes [J].
Fielding, Lee A. ;
Derry, Matthew J. ;
Ladmiral, Vincent ;
Rosselgong, Julien ;
Rodrigues, Aurelie M. ;
Ratcliffe, Liam P. D. ;
Sugihara, Shinji ;
Armes, Steven P. .
CHEMICAL SCIENCE, 2013, 4 (05) :2081-2087
12345678