Synchronous Parotid (Mammary Analog) Secretory Carcinoma and Acinic Cell Carcinoma: Report of a Case

被引：9
作者：
Mossinelli, C. [1 ,2 ]
Pigni, C. [1 ,2 ]
Sovardi, F. [1 ,2 ]
Occhini, A. [1 ,2 ]
Preda, L. [3 ]
Benazzo, M. [1 ,2 ]
Morbini, P. [2 ,4 ]
Pagella, F. [1 ,2 ]
机构：
[1] Univ Pavia, Dept Otolaryngol, Pavia, Italy
[2] Fdn IRCCS Policlin San Matteo, Pavia, Italy
[3] Univ Pavia, Dept Clin Surg Diagnost & Paediat Sci, Pavia, Italy
[4] Univ Pavia, Dept Mol Med, Unit Pathol, Pavia, Italy
来源：
HEAD & NECK PATHOLOGY | 2019年 / 13卷 / 04期
关键词：
MASC; Salivary gland tumor; Cystic carcinoma; Parotid; Acinic cell carcinoma; SALIVARY-GLAND; DIAGNOSIS; UPDATE; TUMORS; MASC; IMMUNOHISTOCHEMISTRY;
D O I：
10.1007/s12105-018-0935-1
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Mammary analogue secretory carcinoma (MASC) is a recently described low-grade salivary gland malignancy with histologic, immunohistochemical and molecular similarities to secretory carcinoma of the breast, including a specific t(12;15)(p13;q25) resulting in an ETV6-NTRK3 gene fusion. Ultrasound and magnetic resonance imaging frequently document a macrocystic structure. The main differential diagnosis of secretory carcinoma is with low grade acinic cell carcinoma (AciCC). The two can be differentiated with immunohistochemical stains for S100, mammaglobin, carbonic anhydrase VI and DOG-1; the identification of the specific translocation can help to characterize non-typical cases. We report a unique case of synchronous MASC and AciCC presenting in a parotid gland and discuss the implications of the correct identification of the two tumors.
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收藏
页码：686 / 691
页数：6
相关论文
共 36 条
[1]   Clinicopathologic and molecular characterization of mammary analogue secretory carcinoma of salivary gland origin [J].
Baghai, F. ;
Yazdani, F. ;
Etebarian, A. ;
Garajei, A. ;
Skalova, A. .
PATHOLOGY RESEARCH AND PRACTICE, 2017, 213 (09) :1112-1118
[2]   Unmasking MASC: Bringing to Light the Unique Morphologic, Immunohistochemical and Genetic Features of the Newly Recognized Mammary Analogue Secretory Carcinoma of Salivary Glands [J].
Bishop J.A. .
Head and Neck Pathology, 2013, 7 (1) :35-39
[3]   Parotid Gland Lesions: Multiparametric Ultrasound and MRI Features [J].
Cantisani, V. ;
David, E. ;
Sidhu, P. S. ;
Sacconi, B. ;
Greco, A. ;
Pandolfi, F. ;
Tombolini, M. ;
Lo Mele, L. ;
Calliada, F. ;
Brunese, L. ;
Catalano, C. ;
De Vincentiis, M. ;
Di Leo, N. ;
Ascenti, G. ;
D'Ambrosio, F. .
ULTRASCHALL IN DER MEDIZIN, 2016, 37 (05) :454-471
[4]   Clinicopathological characterization of mammary analogue secretory carcinoma of salivary glands [J].
Chiosea, Simion I. ;
Griffith, Christopher ;
Assaad, Adel ;
Seethala, Raja R. .
HISTOPATHOLOGY, 2012, 61 (03) :387-394
[5]   Mammary analogue secretory carcinoma (MASC) of the salivary gland: A new tumor entity [J].
Damjanov, Ivan ;
Skenderi, Faruk ;
Vranic, Semir .
BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2016, 16 (03) :237-238
[6]   Use of fluorescent in-situ hybridisation in salivary gland cytology: A powerful diagnostic tool [J].
Evrard, S. M. ;
Meilleroux, J. ;
Daniel, G. ;
Basset, C. ;
Lacoste-Collin, L. ;
Vergez, S. ;
Uro-Coste, E. ;
Courtade-Saidi, M. .
CYTOPATHOLOGY, 2017, 28 (04) :312-320
[7]   Primary Mucoepidermoid Carcinoma Arising from Ectopic Salivary Tissue within an Intraparotid Lymph Node [J].
Faras, Fatemah ;
Abo-Alhassan, Fawaz ;
Bastaki, Jassem ;
Al-Sihan, Mutlaq K. .
CASE REPORTS IN OTOLARYNGOLOGY, 2015, 2015
[8]  
GNEPP DR, 1989, CANCER-AM CANCER SOC, V63, P1219, DOI 10.1002/1097-0142(19890315)63:6<1219::AID-CNCR2820630631>3.0.CO
[9]  
2-Y
[10]   Ultrastructural Characterization of Mammary Analogue Secretory Carcinoma of the Salivary Glands: A Distinct Entity from Acinic Cell Carcinoma? [J].
Guilmette J. ;
Nielsen G.P. ;
Faquin W.C. ;
Selig M. ;
Nosé V. ;
Chi A.W.S. ;
Sadow P.M. .
Head and Neck Pathology, 2017, 11 (4) :419-426
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