Highly divergent cattle hepacivirus N in Southern Brazil

被引：7

作者：

Da Silva, M. S. ^{[1
]}

Weber, M. N. ^{[1
]}

Baumbach, L. F. ^{[1
]}

Cibulski, S. P. ^{[2
]}

Budaszewski, R. F. ^{[1
]}

Mosena, A. C. S. ^{[1
]}

Canova, R. ^{[1
]}

Varela, A. P. M. ^{[3
]}

Mayer, F. Q. ^{[3
]}

Canal, Claudio W. ^{[1
]}

机构：

[1] Univ Fed Rio Grande do Sul, Lab Virol, Fac Vet FAVET, Porto Alegre, RS, Brazil

[2] Univ Fed Paraiba UFPB, Dept Biotechnol, Joao Pessoa, Paraiba, Brazil

[3] Fdn Estadual Pesquisa Agr, Lab Biol Mol, IPVDF, Eldorado Do Sul, RS, Brazil

来源：

ARCHIVES OF VIROLOGY | 2019年 / 164卷 / 12期

关键词：

HEPATITIS-E VIRUS; ANIMAL-MODELS;

D O I：

10.1007/s00705-019-04419-2

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The genus Hepacivirus includes 14 species (Hepacivirus A-N). In this study, we determined a partial genome sequence of a highly divergent bovine hepacivirus (hepacivirus N, HNV) isolate from cattle in Southern Brazil. Previously described HNV isolates have shared 80-99.7% nucleotide sequence identity in the NS3 coding region. However, the sequence determined in this study had 72.6% to 73.8% nucleotide sequence identity to known HNV NS3 sequences. This high divergence could be seen in a phylogenetic tree, suggesting that it represents a new genotype of HNV. These data expand our knowledge concerning the genetic variability and evolution of hepaciviruses.

引用

页码：3133 / 3136

页数：4

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