On-line mid-IR spectroscopy as a real-time approach in monitoring hydrogenation reactions

被引:14
作者
Marziano, I [1 ]
Sharp, DCA [1 ]
Dunn, PJ [1 ]
Hailey, PA [1 ]
机构
[1] Pfizer Ltd, Cent Res, Sandwich CT13 9NJ, Kent, England
关键词
D O I
10.1021/op000030m
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The use of mid-IR. spectroscopy as a real-time monitoring tool for hydrogenation reactions is illustrated. This technique was used for both qualitative and quantitative purposes to monitor the hydrogenation of three different functional groups. The results show that this technique can be successfully used as an alternative to traditional off-line methods to monitor the reaction endpoint and the formation of impurities.
引用
收藏
页码:357 / 361
页数:5
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