Patient hematology during hospitalization for viral pneumonia caused by SARS-CoV-2 and non-SARS-CoV-2 agents: a retrospective study

被引:3
作者
Bai, Bingke [1 ]
Xu, Zhe [2 ]
Hu, Yan [1 ]
Qu, Mengmeng [1 ]
Cheng, Juan [2 ]
Luo, Shengdong [1 ]
Yao, Zengtao [1 ]
Gao, Hongyan [1 ]
Ma, Yenv [1 ]
Gao, Rong [1 ]
Hou, Jun [1 ]
Xin, Shaojie [3 ]
Mao, Panyong [1 ]
机构
[1] Peoples Liberat Army Gen Hosp, Res Ctr Clin & Translat Med, Med Ctr Chinese 5, 100 Middle St,4th West Ring Rd, Beijing 100039, Peoples R China
[2] Peoples Liberat Army Gen Hosp, Med Ctr Chinese 5, Treatment & Res Ctr Infect Dis, 100 Middle St,4th West Ring Rd, Beijing 100039, Peoples R China
[3] Peoples Liberat Army Gen Hosp, Med Ctr Chinese 5, Liver Failure Treatment & Res Ctr, 100 Middle St,4th West Ring Rd, Beijing 100039, Peoples R China
关键词
Hematology; SARS-CoV-2; COVID-19; Adenovirus; ACUTE RESPIRATORY SYNDROME; INFLUENZA-VIRUS; CLINICAL-FEATURES; INFECTION; COVID-19; THROMBOCYTOPENIA; PROTECTION;
D O I
10.1186/s40001-021-00515-9
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background Hematological comparison of coronavirus disease (COVID-19) and other viral pneumonias can provide insights into COVID-19 treatment. Methods In this retrospective case-control single-center study, we compared the data of 126 patients with viral pneumonia during different outbreaks [severe acute respiratory syndrome (SARS) in 2003, influenza A (H1N1) in 2009, human adenovirus type 7 in 2018, and COVID-19 in 2020]. Results One of the COVID-19 characteristics was a continuous decline in the hemoglobin level. The neutrophil count was related to the aggravation of COVID-19 and SARS. Thrombocytopenia occurred in patients with SARS and severe COVID-19 even at the recovery stage. Lymphocytes were related to the entire course of adenovirus infection, recovery of COVID-19, and disease development of SARS. Conclusions Dynamic changes in hematological counts could provide a reference for the pathogenesis and prognosis of pneumonia caused by respiratory viruses in clinics.
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页数:11
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共 41 条
[1]   Neurologic Alterations Due to Respiratory Virus Infections [J].
Bohmwald, Karen ;
Galvez, Nicolas M. S. ;
Rios, Mariana ;
Kalergis, Alexis M. .
FRONTIERS IN CELLULAR NEUROSCIENCE, 2018, 12
[2]   Clinical and immunological features of severe and moderate coronavirus disease 2019 [J].
Chen, Guang ;
Wu, Di ;
Guo, Wei ;
Cao, Yong ;
Huang, Da ;
Wang, Hongwu ;
Wang, Tao ;
Zhang, Xiaoyun ;
Chen, Huilong ;
Yu, Haijing ;
Zhang, Xiaoping ;
Zhang, Minxia ;
Wu, Shiji ;
Song, Jianxin ;
Chen, Tao ;
Han, Meifang ;
Li, Shusheng ;
Luo, Xiaoping ;
Zhao, Jianping ;
Ning, Qin .
JOURNAL OF CLINICAL INVESTIGATION, 2020, 130 (05) :2620-2629
[3]   Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study [J].
Chen, Nanshan ;
Zhou, Min ;
Dong, Xuan ;
Qu, Jieming ;
Gong, Fengyun ;
Han, Yang ;
Qiu, Yang ;
Wang, Jingli ;
Liu, Ying ;
Wei, Yuan ;
Xia, Jia'an ;
Yu, Ting ;
Zhang, Xinxin ;
Zhang, Li .
LANCET, 2020, 395 (10223) :507-513
[4]   Predictive model of diagnosing probable cases of severe acute respiratory syndrome in febrile patients with exposure risk [J].
Chen, SY ;
Su, CP ;
Ma, MHM ;
Chiang, WC ;
Hsu, CY ;
Ko, PCI ;
Tsai, KC ;
Yen, ZS ;
Shih, FY ;
Chen, SC ;
Chen, WJ .
ANNALS OF EMERGENCY MEDICINE, 2004, 43 (01) :1-5
[5]   Respiratory disease caused by a species B2 Adenovirus in a military camp in Turkey [J].
Chmielewicz, B ;
Benzler, J ;
Pauli, G ;
Krause, G ;
Bergmann, F ;
Schweiger, B .
JOURNAL OF MEDICAL VIROLOGY, 2005, 77 (02) :232-237
[6]   Influenza virus replication in macrophages: balancing protection and pathogenesis [J].
Cline, Troy D. ;
Beck, Donald ;
Bianchini, Elizabeth .
JOURNAL OF GENERAL VIROLOGY, 2017, 98 (10) :2401-2412
[7]   Adenoviral Infections in Singapore: Should New Antiviral Therapies and Vaccines Be Adopted? [J].
Coleman, Kristen K. ;
Wong, Chui Ching ;
Jayakumar, Jayanthi ;
Nguyen, Tham T. ;
Wong, Abigail W. L. ;
Yadana, Su ;
Thoon, Koh C. ;
Chan, Kwai Peng ;
Low, Jenny G. ;
Kalimuddin, Shirin ;
Dehghan, Shoaleh ;
Kang, June ;
Shamsaddini, Amirhossein ;
Seto, Donald ;
Su, Yvonne C. F. ;
Gray, Gregory C. .
JOURNAL OF INFECTIOUS DISEASES, 2020, 221 (04) :566-577
[8]   Clinical features, laboratory findings and predictors of death in hospitalized patients with COVID-19 in Sardinia, Italy [J].
De Vito, A. ;
Geremia, N. ;
Fiore, V ;
Princic, E. ;
Babudieri, S. ;
Madeddu, G. .
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2020, 24 (14) :7861-7868
[9]   The Systemic Inflammation Index on Admission Predicts In-Hospital Mortality in COVID-19 Patients [J].
Fois, Alessandro G. ;
Paliogiannis, Panagiotis ;
Scano, Valentina ;
Cau, Stefania ;
Babudieri, Sergio ;
Perra, Roberto ;
Ruzzittu, Giulia ;
Zinellu, Elisabetta ;
Pirina, Pietro ;
Carru, Ciriaco ;
Arru, Luigi B. ;
Fancellu, Alessandro ;
Mondoni, Michele ;
Mangoni, Arduino A. ;
Zinellu, Angelo .
MOLECULES, 2020, 25 (23)
[10]   Neutrophils play an essential role in cooperation with antibody in both protection against and recovery from pulmonary infection with influenza virus in mice [J].
Fujisawa, Haruo .
JOURNAL OF VIROLOGY, 2008, 82 (06) :2772-2783