Properties of novel and widely studied Y-STR loci in three South African populations

被引：21

作者：

Leat, Neil ^{[1
]}

Ehrenreich, Liezle ^{[1
]}

Benjeddou, Mongi ^{[1
]}

Cloete, Kevin ^{[1
]}

Davison, Sean ^{[1
]}

机构：

[1] Univ Western Cape, Dept Biotechnol, ZA-7535 Cape Town, South Africa

来源：

FORENSIC SCIENCE INTERNATIONAL | 2007年 / 168卷 / 2-3期

关键词：

Y chromosome; Y-STR; gene diversity; stutter;

D O I：

10.1016/j.forsciint.2006.07.009

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

The objective of the present study was to examine the properties of a set of single-copy Y-STR loci to assess their suitability for forensic. casework in three South African populations. Three criteria were used to select markers for assessment. Firstly, the single-copy markers of the minimal haplotype were selected based on their established use in forensic studies. Secondly, 8 markers were selected on the basis of high gene diversity values reported for several population studies, and thirdly 19 markers were chosen from a survey of Y-chromosome sequence with selections made primarily on the basis of the number of repeated elements present. Samples were typed from 101 English-speaking Caucasians, 88 Xhosa individuals and 77 Asian Indians. Gene diversity values, the number of alleles identified and the average stutter was determined for each locus. (C) 2006 Elsevier Ireland Ltd. All rights reserved.

引用

页码：154 / 161

页数：8

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