Gadoxetate Disodium-Enhanced MRI of the Liver: Part 1, Protocol Optimization and Lesion Appearance in the Noncirrhotic Liver

被引：254
|
作者：
Ringe, Kristina I. [1 ,2 ]
Husarik, Daniela B. [1 ]
Sirlin, Claude B. [3 ]
Merkle, Elmar M. [1 ]
机构：
[1] Duke Univ, Sch Med, Durham, NC 27710 USA
[2] Hannover Med Sch, Dept Radiol, D-3000 Hannover, Germany
[3] Univ Calif San Diego, Dept Radiol, San Diego, CA 92103 USA
来源：
AMERICAN JOURNAL OF ROENTGENOLOGY | 2010年 / 195卷 / 01期
关键词：
gadoxetate disodium-enhanced MRI; hepatocyte-specific contrast agent; liver lesion; GD-EOB-DTPA; FOCAL NODULAR HYPERPLASIA; ETHOXYBENZYL DIETHYLENETRIAMINEPENTAACETIC ACID; RADIOLOGIC-PATHOLOGICAL CORRELATION; CONTRAST AGENTS; MULTICENTER TRIAL; SPIRAL CT; HISTOPATHOLOGIC FINDINGS; FIBROLAMELLAR CARCINOMA; ORAL-CONTRACEPTIVES;
D O I：
10.2214/AJR.10.4392
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
OBJECTIVE. The purpose of this article is to review the pharmacokinetic and pharmacodynamic properties of gadoxetate disodium (Gd-EOB-DTPA), to describe a workflow-optimized pulse sequence protocol, and to illustrate the imaging appearance of focal lesions in the noncirrhotic liver. CONCLUSION. Gd-EOB-DTPA allows a comprehensive evaluation of the liver with the acquisition of both dynamic and hepatocyte phase images. This provides potential additional information, especially for the detection and characterization of small liver lesions. However, protocol optimization is necessary for improved image quality and workflow.
引用
收藏
页码：13 / 28
页数：16
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