Gadoxetate Disodium-Enhanced MRI of the Liver: Part 1, Protocol Optimization and Lesion Appearance in the Noncirrhotic Liver

被引：254
|
作者：
Ringe, Kristina I. [1 ,2 ]
Husarik, Daniela B. [1 ]
Sirlin, Claude B. [3 ]
Merkle, Elmar M. [1 ]
机构：
[1] Duke Univ, Sch Med, Durham, NC 27710 USA
[2] Hannover Med Sch, Dept Radiol, D-3000 Hannover, Germany
[3] Univ Calif San Diego, Dept Radiol, San Diego, CA 92103 USA
来源：
AMERICAN JOURNAL OF ROENTGENOLOGY | 2010年 / 195卷 / 01期
关键词：
gadoxetate disodium-enhanced MRI; hepatocyte-specific contrast agent; liver lesion; GD-EOB-DTPA; FOCAL NODULAR HYPERPLASIA; ETHOXYBENZYL DIETHYLENETRIAMINEPENTAACETIC ACID; RADIOLOGIC-PATHOLOGICAL CORRELATION; CONTRAST AGENTS; MULTICENTER TRIAL; SPIRAL CT; HISTOPATHOLOGIC FINDINGS; FIBROLAMELLAR CARCINOMA; ORAL-CONTRACEPTIVES;
D O I：
10.2214/AJR.10.4392
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
OBJECTIVE. The purpose of this article is to review the pharmacokinetic and pharmacodynamic properties of gadoxetate disodium (Gd-EOB-DTPA), to describe a workflow-optimized pulse sequence protocol, and to illustrate the imaging appearance of focal lesions in the noncirrhotic liver. CONCLUSION. Gd-EOB-DTPA allows a comprehensive evaluation of the liver with the acquisition of both dynamic and hepatocyte phase images. This provides potential additional information, especially for the detection and characterization of small liver lesions. However, protocol optimization is necessary for improved image quality and workflow.
引用
收藏
页码：13 / 28
页数：16
相关论文
共 50 条
  • [21] The value of gadoxetate disodium-enhanced MR imaging for predicting posthepatectomy liver failure after major hepatic resection: A preliminary study
    Cho, Seung Hyun
    Kang, Ung Rae
    Kim, Joo Dong
    Han, Young Seok
    Choi, Dong Lak
    EUROPEAN JOURNAL OF RADIOLOGY, 2011, 80 (02) : E195 - E200
  • [22] Effect of lapatinib on hepatic parenchymal enhancement on gadoxetate disodium (EOB)-enhanced MRI scans of the rat liver
    Nakamura, Yuko
    Hirokawa, Yutaka
    Kitamura, Shigemi
    Yamasaki, Wataru
    Arihiro, Koji
    Tatsugami, Fuminari
    Iida, Makoto
    Kakizawa, Hideaki
    Date, Shuji
    Awai, Kazuo
    JAPANESE JOURNAL OF RADIOLOGY, 2013, 31 (06) : 386 - 392
  • [23] Predicting microvascular invasion in hepatocellular carcinoma: A dual-institution study on gadoxetate disodium-enhanced MRI
    Jiang, Hanyu
    Wei, Jingwei
    Fu, Fangfang
    Wei, Hong
    Qin, Yun
    Duan, Ting
    Chen, Weixia
    Xie, Kunlin
    Lee, Jeong Min
    Bashir, Mustafa R.
    Wang, Meiyun
    Song, Bin
    Tian, Jie
    LIVER INTERNATIONAL, 2022, 42 (05) : 1158 - 1172
  • [24] Non-focal liver signal abnormalities on hepatobiliary phase of gadoxetate disodium-enhanced MR imaging: a review and differential diagnosis
    Furlan, Alessandro
    Borhani, Amir A.
    Heller, Matthew T.
    Yu, Robinson K.
    Tublin, Mitchell E.
    ABDOMINAL RADIOLOGY, 2016, 41 (07) : 1399 - 1410
  • [25] Detectability of hepatocellular carcinoma by gadoxetate disodium-enhanced hepatic MRI: Tumor-by-tumor analysis in explant livers
    Nakamura, Yuko
    Tashiro, Hirotaka
    Nambu, Junko
    Ohdan, Hideki
    Kakizawa, Hideaki
    Date, Shuji
    Awai, Kazuo
    JOURNAL OF MAGNETIC RESONANCE IMAGING, 2013, 37 (03) : 684 - 691
  • [26] Effect of Flip Angle for Optimization of Image Quality of Gadoxetate Disodium-Enhanced Biliary Imaging at 1.5 T
    Kim, Sooah
    Mussi, Thais C.
    Lee, Lawrence J.
    Mausner, Elizabeth V.
    Cho, Kyunghee C.
    Rosenkrantz, Andrew B.
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2013, 200 (01) : 90 - 96
  • [27] Hepatoblastoma imaging with gadoxetate disodium-enhanced MRI—typical, atypical, pre- and post-treatment evaluation
    Arthur B. Meyers
    Alexander J. Towbin
    James I. Geller
    Daniel J. Podberesky
    Pediatric Radiology, 2012, 42 : 859 - 866
  • [28] Profiling hepatocellular carcinoma aggressiveness with contrast-enhanced ultrasound and gadoxetate disodium-enhanced MRI: An intra-individual comparative study based on the Liver Imaging Reporting and Data System
    Yang, Jie
    Jiang, Hanyu
    Xie, Kunlin
    Bashir, Mustafa R.
    Wan, Haifeng
    Huang, Jiayan
    Qin, Yun
    Chen, Jie
    Lu, Qiang
    Song, Bin
    EUROPEAN JOURNAL OF RADIOLOGY, 2022, 154
  • [29] Comparison of Conventional Gadoxetate Disodium-Enhanced MRI Features and Radiomics Signatures With Machine Learning for Diagnosing Microvascular Invasion
    Chen, Yidi
    Xia, Yuwei
    Tolat, Parag P.
    Long, Liling
    Jiang, Zijian
    Huang, Zhongkui
    Tang, Qin
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2021, 216 (06) : 1510 - 1520
  • [30] Gadoxetate Disodium-Enhanced Hepatic MRI: Dose-Dependent Contrast Dynamics of Hepatic Parenchyma and Portal Vein
    Feuerlein, Sebastian
    Boll, Daniel T.
    Gupta, Rajan T.
    Ringe, Kristina I.
    Marin, Daniele
    Merkle, Elmar M.
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2011, 196 (01) : W18 - W24
12345