Gadoxetate Disodium-Enhanced MRI of the Liver: Part 1, Protocol Optimization and Lesion Appearance in the Noncirrhotic Liver

被引：254
|
作者：
Ringe, Kristina I. [1 ,2 ]
Husarik, Daniela B. [1 ]
Sirlin, Claude B. [3 ]
Merkle, Elmar M. [1 ]
机构：
[1] Duke Univ, Sch Med, Durham, NC 27710 USA
[2] Hannover Med Sch, Dept Radiol, D-3000 Hannover, Germany
[3] Univ Calif San Diego, Dept Radiol, San Diego, CA 92103 USA
来源：
AMERICAN JOURNAL OF ROENTGENOLOGY | 2010年 / 195卷 / 01期
关键词：
gadoxetate disodium-enhanced MRI; hepatocyte-specific contrast agent; liver lesion; GD-EOB-DTPA; FOCAL NODULAR HYPERPLASIA; ETHOXYBENZYL DIETHYLENETRIAMINEPENTAACETIC ACID; RADIOLOGIC-PATHOLOGICAL CORRELATION; CONTRAST AGENTS; MULTICENTER TRIAL; SPIRAL CT; HISTOPATHOLOGIC FINDINGS; FIBROLAMELLAR CARCINOMA; ORAL-CONTRACEPTIVES;
D O I：
10.2214/AJR.10.4392
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
OBJECTIVE. The purpose of this article is to review the pharmacokinetic and pharmacodynamic properties of gadoxetate disodium (Gd-EOB-DTPA), to describe a workflow-optimized pulse sequence protocol, and to illustrate the imaging appearance of focal lesions in the noncirrhotic liver. CONCLUSION. Gd-EOB-DTPA allows a comprehensive evaluation of the liver with the acquisition of both dynamic and hepatocyte phase images. This provides potential additional information, especially for the detection and characterization of small liver lesions. However, protocol optimization is necessary for improved image quality and workflow.
引用
收藏
页码：13 / 28
页数：16
相关论文
共 50 条
  • [1] Gadoxetate Disodium-Enhanced MRI of the Liver: Part 2, Protocol Optimization and Lesion Appearance in the Cirrhotic Liver
    Cruite, Irene
    Schroeder, Michael
    Merkle, Elmar M.
    Sirlin, Claude B.
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2010, 195 (01) : 29 - 41
  • [2] Enhancement patterns and pseudo-washout of hepatic haemangiomas on gadoxetate disodium-enhanced liver MRI
    Kim, Bohyun
    Byun, Jae Ho
    Kim, Hyoung Jung
    Won, Hyung Jin
    Kim, So Yeon
    Shin, Yong Moon
    Kim, Pyo Nyun
    EUROPEAN RADIOLOGY, 2016, 26 (01) : 191 - 198
  • [3] Intraindividual crossover comparison of gadobenate dimeglumine-enhanced and gadoxetate disodium-enhanced MRI for characterizing focal liver lesions
    Tang, Wenjie
    Xiao, Yuanqiang
    Kuang, Sichi
    Rong, Dailin
    He, Bingjun
    Grazioli, Luigi
    Hussain, Shahid M.
    Wang, Jin
    EUROPEAN RADIOLOGY EXPERIMENTAL, 2025, 9 (01)
  • [4] Hepatic Steatosis: Effect on Hepatocyte Enhancement With Gadoxetate Disodium-Enhanced Liver MR Imaging
    Onishi, Hiromitsu
    Theisen, Daniel
    Dietrich, Olaf
    Reiser, Maximilian F.
    Zech, Christoph J.
    JOURNAL OF MAGNETIC RESONANCE IMAGING, 2014, 39 (01) : 42 - 50
  • [5] Quantitative Evaluation of Liver Function with Use of Gadoxetate Disodium-enhanced MR Imaging
    Yamada, Akira
    Hara, Takeshi
    Li, Feng
    Fujinaga, Yasunari
    Ueda, Kazuhiko
    Kadoya, Masumi
    Doi, Kunio
    RADIOLOGY, 2011, 260 (03) : 727 - 733
  • [6] Gadoxetate Disodium-Enhanced Hepatobiliary Phase MRI of Hepatocellular Carcinoma: Correlation With Histological Characteristics
    Choi, Jin-Young
    Kim, Myeong-Jin
    Park, Young Nyun
    Lee, Jeong Min
    Yoo, Sun Kook
    Rha, Sun Young
    Seok, Jae Yeon
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2011, 197 (02) : 399 - 405
  • [7] Troubleshooting Arterial-Phase MR Images of Gadoxetate Disodium-Enhanced Liver
    Huh, Jimi
    Kim, So Yeon
    Yeh, Benjamin M.
    Lee, Seung Soo
    Kim, Kyoung Won
    Wu, En-Haw
    Wang, Z. Jane
    Zhao, Li-qin
    Chang, Wei Chou
    KOREAN JOURNAL OF RADIOLOGY, 2015, 16 (06) : 1207 - 1215
  • [8] Transient Severe Motion Artifact Related to Gadoxetate Disodium-Enhanced Liver MRI: Frequency and Risk Evaluation at a German Institution
    Well, Lennart
    Rausch, Vanessa Hanna
    Adam, Gerhard
    Henes, Frank Oliver
    Bannas, Peter
    ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 2017, 189 (07): : 651 - 660
  • [9] Features of acute liver congestion on gadoxetate disodium-enhanced MRI in a rat model: Role of organic anion-transporting polypeptide 1A1
    Shimizu, Akira
    Kobayashi, Akira
    Motoyama, Hiroaki
    Sakai, Hiroshi
    Yamada, Akira
    Yoshizawa, Akihiko
    Momose, Masanobu
    Kadoya, Masumi
    Miyagawa, Shin-ichi
    JOURNAL OF MAGNETIC RESONANCE IMAGING, 2015, 42 (03) : 828 - 836
  • [10] Gadoxetate Disodium-Enhanced MRI to Differentiate Dysplastic Nodules and Grade of Hepatocellular Carcinoma: Correlation With Histopathology
    Channual, Stephanie
    Tan, Nelly
    Siripongsakun, Surachate
    Lassman, Charles
    Lu, David S.
    Raman, Steven S.
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2015, 205 (03) : 546 - 553
12345