3-Chloro-6-{4-[3-(trifluoromethyl)-phenyl]piperazin-1-yl}pyridazine

被引：0
作者：
Arslan, Hakan [1 ,2 ]
Utku, Semra [3 ]
Hardcastle, Kenneth I. [1 ]
Gokce, Mehtap [4 ]
Lense, Sheri [1 ]
机构：
[1] Emory Univ, Dept Chem, Atlanta, GA 30322 USA
[2] Mersin Univ, Fac Arts & Sci, Dept Chem, TR-33343 Mersin, Turkey
[3] Mersin Univ, Fac Pharm, Dept Pharmaceut Sci, TR-33169 Mersin, Turkey
[4] Gazi Univ, Fac Pharm, Dept Pharmaceut Sci, TR-06330 Ankara, Turkey
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2010年 / 66卷
关键词：
ANTIINFLAMMATORY ACTIVITY; DERIVATIVES; AGENTS;
D O I：
10.1107/S1600536810004137
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The title compound, C15H14ClF3N4, was synthesized from 3,6-dichloropyridazine and 1-[3-(trifluoromethyl) phenyl] piperazine. The piperazine ring is flanked by 3-chloropyridazine and 3-trifluoromethylphenyl rings and adopts a chair conformation, whereas the 3-chloropyridazine and 3-trifluoromethylphenyl rings are planar, with maximum deviations of 0.0069 (13) and 0.0133 (14) angstrom respectively. The crystal structure is stabilized by weak intermolecular C-H center dot center dot center dot N hydrogen-bond interactions.
引用
收藏
页码：O532 / U4263
页数：11
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