Novel thieno oxazine analogues as antihyperglycemic and lipid modulating agents

被引：11
作者：
Das, SK
Reddy, KA
Abbineni, C
Iqbal, J
Suresh, J
Premkumar, M
Chakrabarti, R
机构：
[1] Dr Reddys Res Fdn, Discovery Chem, Hyderabad 500050, Andhra Pradesh, India
[2] Dr Reddys Res Fdn, Discovery Biol, Hyderabad 500050, Andhra Pradesh, India
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2003年 / 13卷 / 03期
关键词：
D O I：
10.1016/S0960-894X(02)00976-9
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A series of phenyl acetic acid and alpha-hydroxy propionic acid derivatives were synthesized. In vivo studies of the compounds indicated compound 2c as the most potent in one of the series, which has both glucose and lipid lowering properties. The syntheses and biological studies have been discussed. (C) 2002 Elsevier Science Ltd. All rights reserved.
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页码：399 / 403
页数：5
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