Molecular biology and colorectal cancer.

被引：0

作者：

Laurent-Puig, P ^{[1
]}

Cugnenc, PH ^{[1
]}

机构：

[1] Hop Laennec, Serv Chirurg Digest Oncol & Gen, F-75007 Paris, France

来源：

JOURNAL DE CHIRURGIE | 1997年 / 134卷 / 7-8期

关键词：

colorectal cancer; genetic alteration; mutation;

D O I：

暂无

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

New technologies in molecular biology will allow the improvement of screening, diagnosis and prognosis of colorectal cancer patients. For example the determination of germline mutation in APC or in mismatch repair genes in patient with familial adenomatous polyposis or with HNPCC is now possible. The clinical surveillance can be restricted to the patients with these germline defects. More over the knowledge of somatic genetic alterations in colorectal cancer cells seems to be useful in the determination of prognosis of these patients or in order to predict the chemotherapy response.

引用

页码：279 / 282

页数：4

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