REPURPOSED TRADITIONAL MEDICINAL PLANTS AS AN IMPORTANT WEAPON FOR FIGHTING AGAINST COVID-19: PAKISTANI PERSPECTIVE

被引:2
作者
Arshad, Bushra [1 ,2 ]
机构
[1] Minist Sci & Technol Islamabad, Pakistan Council Sci & Technol, Islamabad, Pakistan
[2] Univ Agr Faisalabad, Dept Biochem, Faisalabad, Pakistan
关键词
TMPs; SARS-COV2; Manifestations; Inflammation; Adjunctive treatment and Vitamins; IN-VITRO; BIOLOGICAL-ACTIVITIES; ANTIVIRAL ACTIVITY; MAIN PROTEASE; VITAMIN-C; EXTRACT; VIRUS; BRONCHODILATOR; IDENTIFICATION; ANTIINFLUENZA;
D O I
10.30848/PJB2022-4(2)
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
In present scenario, World needs prevention and control of SARS-COV2 ailment epidemic. To manage overall sheer carrier and sufferers of covid-19 needs intensive medical assistance and adjunctive treatment plans to overcome the malady. The outbreak can be coped with support of ailment suppression through public fitness measures and adjunctive treatments for patients. In Pakistan due to scarce health care amenities, most of the rural population rely upon indigenous traditional medicinal plant (TMPs) resources. Due to lack of proper anti-covid-19 therapy, TMPs/herbal treatments could be helpful as first line of defence. It is indispensable to securitize potent repurposed TMPS to impede viral entry, viral proliferation manifestations, inflammation and immunity booster as major weapons against the COVID-19. However, most of these TMPs are being examined in a lot of molecular docking analysis, In vitro In vivo experimentation and in clinical trials at various levels. Auxiliary to this, review describes current hallmark of vitamins research in efficient functioning of immune system. This overview suggested that traditional medicinal plants are safe and have enough hierarchy of evidence to use them as adjunctive treatment. This review compiles, the medicinal plants with potent bioactive compounds to devise fast and sensitive adjunctive therapy and for further planning to explore suitable candidates for drug development.
引用
收藏
页码:1495 / 1505
页数:11
相关论文
共 91 条
[1]   Moroccan Medicinal plants as inhibitors against SARS-CoV-2 main protease: Computational investigations [J].
Aanouz, I. ;
Belhassan, A. ;
El-Khatabi, K. ;
Lakhlifi, T. ;
El-Idrissi, M. ;
Bouachrine, M. .
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2021, 39 (08) :2971-2979
[2]   Antiviral, antifungal, and insecticidal activities of Eucalyptus bark extract: HPLC analysis of polyphenolic compounds [J].
Abdelkhalek, Ahmed ;
Salem, Mohamed Z. M. ;
Kordy, Ahmed M. ;
Salem, Abdelfattah Z. M. ;
Behiry, Said, I .
MICROBIAL PATHOGENESIS, 2020, 147
[3]  
Ahmad Aftab, 2013, Asian Pacific Journal of Tropical Biomedicine, V3, P337, DOI 10.1016/S2221-1691(13)60075-1
[4]   Antiviral potential of medicinal plants against HIV, HSV, influenza, hepatitis, and coxsackievirus: A systematic review [J].
Akram, Muhammad ;
Tahir, Imtiaz Mahmood ;
Shah, Syed Muhammad Ali ;
Mahmood, Zahed ;
Altaf, Awais ;
Ahmad, Khalil ;
Munir, Naveed ;
Daniyal, Muhammad ;
Nasir, Suhaila ;
Mehboob, Huma .
PHYTOTHERAPY RESEARCH, 2018, 32 (05) :811-822
[5]   Traditional medicinal plants used for respiratory disorders in Pakistan: a review of the ethno-medicinal and pharmacological evidence [J].
Alamgeer ;
Younis, Waqas ;
Asif, Hira ;
Sharif, Amber ;
Riaz, Humayun ;
Bukhari, Ishfaq Ali ;
Assiri, Asaad Mohamed .
CHINESE MEDICINE, 2018, 13
[6]   Early Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19 [J].
Alexander, Jan ;
Tinkov, Alexey ;
Strand, Tor A. ;
Alehagen, Urban ;
Skalny, Anatoly ;
Aaseth, Jan .
NUTRIENTS, 2020, 12 (08) :1-12
[7]   Integrative considerations during the COVID-19 pandemic [J].
Alschuler, Lise ;
Weil, Andrew ;
Horwitz, Randy ;
Stamets, Paul ;
Chiasson, Ann Marie ;
Crocker, Robert ;
Maizes, Victoria .
EXPLORE-THE JOURNAL OF SCIENCE AND HEALING, 2020, 16 (06) :354-356
[8]   Analysis of bioactive composites and antiviral activity of Iresine herbstii extracts against Newcastle disease virus in ovo [J].
Andleeb, Rahat ;
Ashraf, Asma ;
Muzammil, Saima ;
Naz, Shabana ;
Asad, Farkhanda ;
Ali, Tayyaba ;
Rafi, Rida ;
Al-Ghanim, K. A. ;
Al-Misned, F. ;
Ahmed, Z. ;
Mahboob, Shahid .
SAUDI JOURNAL OF BIOLOGICAL SCIENCES, 2020, 27 (01) :335-340
[9]   Severe Acute Respiratory Syndrome Coronavirus Nonstructural Proteins 3, 4, and 6 Induce Double-Membrane Vesicles [J].
Angelini, Megan M. ;
Akhlaghpour, Marzieh ;
Neuman, Benjamin W. ;
Buchmeier, Michael J. .
MBIO, 2013, 4 (04)
[10]   Middle East Respiratory Syndrome [J].
Arabi, Yaseen M. ;
Balkhy, Hanan H. ;
Hayden, Frederick G. ;
Bouchama, Abderrezak ;
Luke, Thomas ;
Baillie, J. Kenneth ;
Al-Omari, Awad ;
Hajeer, Ali H. ;
Senga, Mikiko ;
Denison, Mark R. ;
Nguyen-Van-Tam, Jonathan S. ;
Shindo, Nahoko ;
Bermingham, Alison ;
Chappell, James D. ;
Van Kerkhove, Maria D. ;
Fowler, Robert A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (06) :584-594