Primary cutaneous nocardiosis of the head and neck in an immunocompetent patient

被引:4
作者
Acevedo, Claudio Tirso [1 ]
Imkamp, Frank [2 ]
Maggio, Ewerton Marques [3 ]
Brugger, Silvio Daniel [1 ]
机构
[1] Univ Zurich, Univ Hosp Zurich, Div Infect Dis & Hosp Epidemiol, Zurich, Switzerland
[2] Univ Zurich, Dept Med Microbiol, Zurich, Switzerland
[3] Univ Hosp Zurich, Inst Pathol & Mol Pathol, Zurich, Switzerland
关键词
infectious diseases; dermatology; IDENTIFICATION;
D O I
10.1136/bcr-2020-241217
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Nocardiosis is known to be an opportunistic infection most commonly affecting immunocompromised patients that can lead to life-threatening conditions. Primary cutaneous disease remains a rare manifestation and unlike pulmonary or disseminated nocardiosis, it usually affects immunocompetent individuals. We present a case of a primary cutaneous nocardiosis of the head and neck after an insect bite in a healthy 50-year-old woman who had recently travelled from Greece. She presented with a painful right-sided swelling of her face and neck and an ulcerated plaque over the right temple. Biopsy of the plaque revealed inflammation with abscess formation indicating underlying infection. Culture from the biopsy showed growth of Nocardia spp and 16S rRNA gene sequence analysis identified Nocardia brasiliensis. The patient was treated with trimethoprim/sulfamethoxazole and subsequently switched to amoxicillin/clavulanic acid due to a drug eruption. Antibiotic therapy was continued for a total of 3 months with complete resolution of the skin lesions.
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页数:4
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