Systemic Scleroderma-Definition, Clinical Picture and Laboratory Diagnostics

被引:17
作者
Kowalska-Kepczynska, Anna [1 ]
机构
[1] Med Univ Lublin, Dept Biochem Diagnost, Chair Lab Diagnost, PL-20081 Lublin, Poland
关键词
systemic scleroderma; connective tissue disease; laboratory diagnostic; INTERSTITIAL LUNG-DISEASE; PRIMARY MYOCARDIAL INVOLVEMENT; DIFFUSE ALVEOLAR HEMORRHAGE; STEM-CELL TRANSPLANTATION; C-REACTIVE PROTEIN; SCLEROSIS PATIENTS; TOPOISOMERASE-I; RENAL CRISIS; GASTROINTESTINAL INVOLVEMENT; THROMBOTIC MICROANGIOPATHY;
D O I
10.3390/jcm11092299
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
(1) Background: Scleroderma (Sc) is a rare connective tissue disease classified as an autoimmune disorder. The pathogenesis of this disease is not fully understood. (2) Methods: This article reviews the literature on systemic scleroderma (SSc). A review of available scientific articles was conducted using the PubMed database with a time range of January 1985 to December 2021. (3) Results and Conclusions: The article is a review of information on epidemiology, criteria for diagnosis, pathogenesis, a variety of clinical pictures and the possibility of laboratory diagnostic in the diagnosis and monitoring of systemic scleroderma.
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页数:21
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