Provisioning the origin and early evolution of life
被引:32
|
作者:
Wu, Long-Fei
论文数: 0引用数: 0
h-index: 0
机构:
Med Res Council Lab Mol Biol, Francis Crick Ave, Cambridge CB2 0QH, EnglandMed Res Council Lab Mol Biol, Francis Crick Ave, Cambridge CB2 0QH, England
Wu, Long-Fei
[1
]
Sutherland, John D.
论文数: 0引用数: 0
h-index: 0
机构:
Med Res Council Lab Mol Biol, Francis Crick Ave, Cambridge CB2 0QH, EnglandMed Res Council Lab Mol Biol, Francis Crick Ave, Cambridge CB2 0QH, England
Sutherland, John D.
[1
]
机构:
[1] Med Res Council Lab Mol Biol, Francis Crick Ave, Cambridge CB2 0QH, England
There is a lot of controversy in the origin and early evolution of life field, but most people agree that at the advent of genetically coded protein synthesis, cells must have had access to ribonucleotides, amino acids, lipids and some sort of energy source. However, the provenance of these materials is a contentious issue - did early life obtain its building blocks prefabricated from the environment, or did it synthesise them from feedstocks such as CO2 and N-2? In the first case, synthesis conditions need not have been compatible with life and any kind of reaction network that furnished the building blocks - and not much else - could have provisioned the subsequent origin and early evolution of life. In the second case, synthesis must have been under life-compatible conditions, with the reaction network either along the same lines as extant biology or along different ones. On the basis of experimental evidence, we will argue in favour of prefabrication and against synthesis by life in its nascent state, especially synthesis that resembles extant biosynthesis, which we suggest would have been well-nigh impossible without biological catalysts.
机构:
Univ Lyon, Claude Bernard Lyon 1, Inst Chim & Biochim Mol & Supramol, Batiment Lederer,Bur 11-002,1 Rue Victor Grignard, F-69622 Villeurbanne, FranceUniv Lyon, Claude Bernard Lyon 1, Inst Chim & Biochim Mol & Supramol, Batiment Lederer,Bur 11-002,1 Rue Victor Grignard, F-69622 Villeurbanne, France
机构:
Univ Wisconsin, Dept Bot, Madison, WI 53706 USA
Univ Wisconsin, Wisconsin Inst Discovery, Madison, WI 53706 USAUniv Wisconsin, Dept Bot, Madison, WI 53706 USA
机构:
Oberlin Coll & Conservatory, Dept Biol, Oberlin, OH 44074 USA
Blue Marble Space Inst Sci, Seattle, WA 98154 USAOberlin Coll & Conservatory, Dept Biol, Oberlin, OH 44074 USA
Goldman, Aaron D.
Kacar, Betul
论文数: 0引用数: 0
h-index: 0
机构:
Blue Marble Space Inst Sci, Seattle, WA 98154 USA
Univ Arizona, Dept Mol & Cellular Biol, Tucson, AZ 85721 USA
Univ Arizona, Lunar & Planetary Lab, Tucson, AZ 85721 USA
Univ Arizona, Dept Astron, Tucson, AZ 85721 USA
Tokyo Inst Technol, Earth Life Sci Inst, Meguro Ku, Tokyo 1528550, JapanOberlin Coll & Conservatory, Dept Biol, Oberlin, OH 44074 USA